Evidence mapPaperPMID 35683378Full record

ArticleJournal of clinical medicine2022

Prognostic Value of Cardiac Troponin I in Patients with Ventricular Tachyarrhythmias.

Ibrahim Akin, Michael Behnes, Julian Müller, Jan Forner, Mohammad Abumayyaleh, Kambis Mashayekhi, Muharrem Akin, Thomas Bertsch, Kathrin Weidner, Jonas Rusnak and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Ibrahim AkinFirst Department of Medicine, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Michael BehnesFirst Department of Medicine, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany.ORCID 0000-0001-5970-0093
Julian MüllerClinic for Interventional Electrophysiology, Heart Centre Bad Neustadt, 97616 Bad Neustadt a. d. Saale, Germany.ORCID 0000-0001-8793-3134
Jan FornerFirst Department of Medicine, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Mohammad AbumayyalehFirst Department of Medicine, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Kambis MashayekhiDepartment of Internal Medicine and Cardiology, Mediclin Heart Centre Lahr, 77933 Lahr, Germany.
Muharrem AkinDepartment of Cardiology and Angiology, Hannover Medical School, 30625 Hannover, Germany.
Thomas BertschInstitute of Clinical Chemistry, Laboratory Medicine and Transfusion Medicine, Nuremberg General Hospital, Paracelsus Medical University, 90419 Nuremberg, Germany.
Kathrin WeidnerFirst Department of Medicine, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Jonas RusnakFirst Department of Medicine, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Dirk Große MeininghausDepartment of Cardiology, Carl-Thiem-Klinikum Cottbus, 03048 Cottbus, Germany.
Maximilian KittelInstitute for Clinical Chemistry, Faculty of Medicine Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Tobias SchuppFirst Department of Medicine, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany.ORCID 0000-0001-8171-7617
Heidelberg University · DECarl-Thiem-Klinikum Cottbus · DEMedizinische Hochschule Hannover · DENuremberg Hospital · DERhön-Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Besides the diagnostic role in acute myocardial infarction, cardiac troponin I levels (cTNI) may be increased in various other clinical conditions, including heart failure, valvular heart disease and sepsis. However, limited data are available regarding the prognostic role of cTNI in the setting of ventricular tachyarrhythmias. Therefore, the present study sought to assess the prognostic impact of cTNI in patients with ventricular tachyarrhythmias (i.e., ventricular tachycardia (VT) and fibrillation (VF)) on admission. A large retrospective registry was used, including all consecutive patients presenting with ventricular tachyarrhythmias from 2002 to 2015. The prognostic impact of elevated cTNI levels was investigated for 30-day all-cause mortality (i.e., primary endpoint) using Kaplan-Meier, receiver operating characteristic (ROC), multivariable Cox regression analyses and propensity score matching. From a total of 1104 patients with ventricular tachyarrhythmias and available cTNI levels on admission, 46% were admitted with VT and 54% with VF. At 30 days, high cTNI was associated with the primary endpoint (40% vs. 22%; log rank

Indexed as

biomarkerscardiac troponin Icoronary artery diseasesudden cardiac deathventricular tachyarrhythmias

Identifiers

PMID35683378
PMCPMC9181556
OpenAlexW4281475964

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.