Evidence map›Paper›PMID 35684376›Full record

ReviewMolecules (Basel, Switzerland)2022

Selected Species of the Cucurbitaceae Family Used in Mexico for the Treatment of Diabetes Mellitus.

Maira Huerta-Reyes, Rosario Tavera-Hernández, J Javier Alvarado-Sansininea, Manuel Jiménez-Estrada

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Hydroalcoholic Extracts ofMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Foods (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Review
  6. RSC advances · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Frontiers in nutrition · 2023
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Maira Huerta-ReyesUnidad de Investigación Médica en Enfermedades Nefrológicas, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Cuauhtémoc, Ciudad de México 06720, Mexico.ORCID 0000-0003-1133-5044
Rosario Tavera-HernándezInstituto de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, Ciudad de México 04510, Mexico.ORCID 0000-0001-5501-2496
J Javier Alvarado-SansinineaHerbario FEZA, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Batalla de 5 de Mayo S/N, Col. Ejército de Oriente, Ciudad de México 09230, Mexico.
Manuel Jiménez-EstradaInstituto de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, Ciudad de México 04510, Mexico.ORCID 0000-0001-6187-4877
Universidad Nacional Autónoma de México · MXMexican Social Security Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Mexico, Diabetes mellitus (DM) is a serious health problem, and although the current pharmacological treatments for DM such as insulin and oral hypoglycemics are available, the Mexican population continues to use medicinal plants in the treatment of DM. The antidiabetic properties of the plant species that belong to the Cucurbitaceae family has already been recognized worldwide. Since Mexico is one of the most important centers of diversity of Cucurbitaceae, the present work contributes to the review of the most used species of Cucurbitaceae in the treatment of DM in Mexico. The reviewed species (Cucurbita ficifolia, C. maxima, C. moschata, C. pepo, Ibervillea sonorae, Sechium edule, Citrullus lanatus, Cucumis melo, and C. sativus) revealed that the antidiabetic effects exerted are effective in a number of mechanisms involved in the complex pathogenesis of DM: hypoglycemic, antioxidant, anti-inflammatory, anti-obesity, protective effects on diverse organs and cells, as well as in the control of dyslipidemias; furthermore, the select species of the Cucurbitaceae family could also be essential components of diets for the control of DM in patients with the disease. Thus, the Cucurbitaceae species selected in the present work represent a source of antidiabetic agents that perhaps establish the bases for novel clinical treatments.

Indexed as

CucurbitaceaeDiabetes MellitusHumansHypoglycemic AgentsInsulinMexicoHypoglycemic AgentsInsulinantidiabeticanti-inflammatoryantioxidantCucurbitaceaeDiabetes mellitushypoglycemictraditional mexican medicineα-amylaseα-glucosidase

Identifiers

PMID35684376
PMCPMC9182361
OpenAlexW4281800171

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.