Evidence map›Paper›PMID 35685772›Full record

ReviewFrontiers in neuroscience2022

PET Imaging in Animal Models of Alzheimer's Disease.

Baosheng Chen, Bernadette Marquez-Nostra, Erika Belitzky, Takuya Toyonaga, Jie Tong, Yiyun Huang, Zhengxin Cai

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Comparative study ofBMC neuroscience · 2025
    Article
  7. Article
  8. Review
  9. Evaluation of [Receptors (Basel, Switzerland) · 2025
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Baosheng ChenPET Center, Radiology, Yale School of Medicine, New Haven, CT, United States.
Bernadette Marquez-NostraPET Center, Radiology, Yale School of Medicine, New Haven, CT, United States.
Erika BelitzkyPET Center, Radiology, Yale School of Medicine, New Haven, CT, United States.
Takuya ToyonagaPET Center, Radiology, Yale School of Medicine, New Haven, CT, United States.
Jie TongPET Center, Radiology, Yale School of Medicine, New Haven, CT, United States.
Yiyun HuangPET Center, Radiology, Yale School of Medicine, New Haven, CT, United States.
Zhengxin CaiPET Center, Radiology, Yale School of Medicine, New Haven, CT, United States.

Funding

Development of PET imaging probes for ROCK2R01AG069921 · NIA · YALE UNIVERSITY · PI CAI, ZHENGXIN · 2021 to 2023
$2.5M
Development of Novel SV2A PET Agents for Early Detection of Alzheimers DiseaseR01AG058773 · NIA · YALE UNIVERSITY · PI CAI, ZHENGXIN · 2018 to 2020
$2.4M
NIA NIH HHS R01 AG058773NIA NIH HHS R01 AG069921
6 · The paper itself

Abstract

The successful development and translation of PET imaging agents targeting β-amyloid plaques and hyperphosphorylated tau tangles have allowed for

Indexed as

Alzheimer’s diseaseanimal modelneurodegenerationneuroinflamamationpositron emission tomographySV2Atauβ-amyloid (Aβ)

Identifiers

PMID35685772
PMCPMC9171374
OpenAlexW4281389716

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.