Evidence map›Paper›PMID 35686124›Full record

ArticleFrontiers in immunology2022

Paeonol Interferes With Quorum-Sensing in

Huaqiao Tang, Dan Yang, Ling Zhu, Fei Shi, Gang Ye, Hongrui Guo, Huidan Deng, Ling Zhao, Zhiwen Xu, Yinglun Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Multidrug-resistantVirulence · 2025
    Review
  4. Article
  5. The role of cyano-phycocyanin as a quorum sensing inhibitor to attenuateFrontiers in cellular and infection microbiology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Spiramycin DisarmsAntibiotics (Basel, Switzerland) · 2023
    Article
  14. TargetingFrontiers in cellular and infection microbiology · 2023
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Huaqiao TangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Dan YangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ling ZhuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Fei ShiCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Gang YeCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Hongrui GuoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Huidan DengCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ling ZhaoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Zhiwen XuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yinglun LiCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Sichuan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing quorum-sensing (QS) based anti-infection drugs is one of the most powerful strategies to combat multidrug-resistant bacteria. Paeonol has been proven to attenuate the QS-controlled virulence factors of

Indexed as

Pseudomonas aeruginosaVirulence FactorsAcetophenonesAnimalsAnti-Inflammatory AgentsCytokinesInflammationMiceAcetophenonesAnti-Inflammatory AgentsCytokinespaeonolVirulence FactorsinflammationpaeonolP. aeruginosaquorum sensingRAW264.7

Identifiers

PMID35686124
PMCPMC9170885
OpenAlexW4281382365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.