Evidence map›Paper›PMID 35689870›Full record

ReviewCurrent opinion in pharmacology2022

Mucus-targeting therapies of defective mucus clearance for cystic fibrosis: A short review.

Miriam Frankenthal Figueira, Carla M P Ribeiro, Brian Button

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Normalization of Muc5b ameliorates airway mucus plugging during persistentAmerican journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  11. Emerging cell and molecular targets for treating mucus hypersecretion in asthma.Allergology international : official journal of the Japanese Society of Allergology · 2024
    Review
  12. Review
  13. Review
  14. Towards a better mucolytic.The European respiratory journal · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Miriam Frankenthal FigueiraMarsico Lung Institute/Cystic Fibrosis Center, University of North Carolina, Chapel Hill, NC, 27599-7248, USA.
Carla M P RibeiroMarsico Lung Institute/Cystic Fibrosis Center, University of North Carolina, Chapel Hill, NC, 27599-7248, USA; Department of Medicine, University of North Carolina, Chapel Hill, NC, 27599-7248, USA; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, 27599-7248, USA.
Brian ButtonMarsico Lung Institute/Cystic Fibrosis Center, University of North Carolina, Chapel Hill, NC, 27599-7248, USA; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC, 27599-7248, USA. Electronic address: brian_button@med.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Scott H Randell · 2004 to 2026
$26.5M
The role of mucus and pulmonary surface interactions in lung defenseR01HL125280 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUTTON, BRIAN M · 2015 to 2023
$3.1M
NHLBI NIH HHS R01 HL125280NIDDK NIH HHS P30 DK065988
6 · The paper itself

Abstract

In the lungs, defective CFTR associated with cystic fibrosis (CF) represents the nidus for abnormal mucus clearance in the airways and consequently a progressive lung disease. Defective CFTR-mediated Cl

Indexed as

Cystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorHumansLungMucusCystic Fibrosis Transmembrane Conductance Regulator

Identifiers

PMID35689870
PMCPMC9891491
OpenAlexW4281771458

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.