Metformin × glycemic control

SynthesisFrontiers in endocrinology2022

The Association Between Antidiabetic Agents and Clinical Outcomes of COVID-19 Patients With Diabetes: A Bayesian Network Meta-Analysis.

Yidan Chen et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 2022

No range given

Reported lower glycemic control, no range given

−26%

Bigger than 2 in 10 for glycemic control

As reported

OR 0.74, no interval

No range given

Reported lower glycemic control, no range given

−12%

Bigger than 1 in 10 for glycemic control

As reported

OR 0.88, no interval

No range given

Reported lower glycemic control, no range given

−18%

Bigger than 1 in 10 for glycemic control

As reported

OR 0.82, no interval

No range given

Reported lower deaths, no range given

−3%

Bigger than 1 in 10 for all-cause mortality

As reported

OR 0.97, no interval · the paper's word: All-cause mortality

+3 more in the walkthrough ↓

Seven numbers in the abstract

the abstract, start to end

Metformin (odds ratio (OR), 0.74; P=0.001), dipeptidyl peptidase-4 inhibitors (DPP4i) (OR, 0.88; P=0.04), sodium-glucose cotransporter-2 inhibitors (SGLT2i) (OR, 0.82; P=0.001), and glucagon-like peptide-1 receptor agonists (GLP1RA) (OR, 0.91; P=0.02) treatment were

resulted in higher mortality (OR, 1.8; P=0.001).

differ in sulfonylurea (OR, 0.97; P=0.56) and thiazolidinediones (TZDs) (OR, 1.00; P=0.96) users.

← favours treatmentfavours comparator →
could be chance
No interval given · direction only, strength unknown
Glycemic control
OR 0.74
Glycemic control
OR 0.88
Glycemic control
OR 0.82
Glycemic control
OR 0.91
All-cause mortality
OR 1.8
All-cause mortality
OR 0.97
All-cause mortality
OR 1.00
MetforminThiazolidinedionesInsulinGlycemic controlAll-cause mortality
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Full record →Abstract, authors, funding and every citing paper · PMID 35692410