Evidence map›Paper›PMID 35694288›Full record

ArticleFrontiers in microbiology2022

Comparison of Microbial Populations in the Blood of Patients With Myocardial Infarction and Healthy Individuals.

Ikram Khan, Imran Khan, Mian Adnan Kakakhel, Zhang Xiaowei, Mao Ting, Ikram Ali, Yu Fei, Zhou Jianye, Li Zhiqiang, An Lizhe

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Pathological Alterations in Human Blood Microbiome-An Updated Review.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ikram KhanSchool of Life Sciences, Lanzhou University, Lanzhou, China.
Imran KhanDepartment of Microbiology, Khyber Medical University Peshawar, Peshawar, Pakistan.
Mian Adnan KakakhelSchool of Life Sciences, Lanzhou University, Lanzhou, China.
Zhang XiaoweiLanzhou University Second Hospital, Lanzhou, China.
Mao TingLanzhou University Second Hospital, Lanzhou, China.
Ikram AliSchool of Life Sciences, Lanzhou University, Lanzhou, China.
Yu FeiSchool of Stomatology, Northwest Minzu University, Lanzhou, China.
Zhou JianyeSchool of Stomatology, Northwest Minzu University, Lanzhou, China.
Li ZhiqiangSchool of Stomatology, Northwest Minzu University, Lanzhou, China.
An LizheSchool of Life Sciences, Lanzhou University, Lanzhou, China.
Lanzhou University · CNMinzu University of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased bacterial translocation in the gut and bloodstream infections are both major comorbidities of heart failure and myocardial infarction (MI). However, the alterations in the microbiome of the blood of patients with MI remain unclear. To test this hypothesis, we conducted this case-control study to explore the microbiota compositions in the blood of Chinese patients with MI. Using high-throughput Illumina HiSeq sequencing targeting the V3-V4 region of the 16S ribosomal RNA (rRNA) gene, the microbiota communities in the blood of 29 patients with MI and 29 healthy controls were examined. In addition, the relationship between the blood microbiome and clinical features of MI was investigated. This study revealed a significant reduction in alpha diversity (Shannon index) in the MI group compared with the healthy controls. Also, a significant difference was detected in the structure and richness between the patients with MI and healthy controls. The members of the phylum Actinobacteria, class Actinobacteria, order Bifdobacteriales, family Bifidobacteriaceae, and genus

Indexed as

bacteriablood circulationfunctional analysisHiSeqmyocardial infarction

Identifiers

PMID35694288
PMCPMC9176212
OpenAlexW4281477687

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.