Evidence map›Paper›PMID 35695557›Full record

ArticleAnnals of medicine2022

Prognostic value of systemic inflammatory response index in patients with acute coronary syndrome undergoing percutaneous coronary intervention.

Kangning Han, Dongmei Shi, Lixia Yang, Zhijian Wang, Yueping Li, Fei Gao, Yuyang Liu, Xiaoteng Ma, Yujie Zhou

Abstract read
In one paragraph

Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. The Role of Systemic Inflammatory Indices in Predicting Composite Adverse Outcomes of Peripartum Hemorrhage Treated with Fibrinogen Concentrate.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Kangning HanBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Dongmei ShiBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Lixia YangBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Zhijian WangBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yueping LiBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Fei GaoBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yuyang LiuBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xiaoteng MaBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yujie ZhouBeijing Anzhen Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe systemic inflammatory response index (SIRI) is a novel inflammatory biomarker in many diseases.

objectivesThe aim of this study was to examine the association between SIRI and adverse events in patients with the acute coronary syndrome (ACS) undergoing percutaneous coronary intervention.

methodsA total of 1724 patients with ACS enrolled from June 2016 to November 2017 at a single centre were included in this study, and SIRI was calculated for each patient. The primary endpoint was the composite of major adverse cardiovascular events (MACE), including overall death, non-fatal myocardial infarction, non-fatal stroke, and unplanned repeat revascularization.

resultsDuring a median follow-up of 927 days, 355 patients had MACE. Multivariate Cox analysis showed that SIRI was significantly associated with MACE (hazard ratio: 1.127, 95% confidence interval: 1.034-1.229

conclusionSIRI was an independent risk factor for MACE and provided incremental prognostic information in patients with ACS undergoing percutaneous coronary intervention. KEY MESSAGESThe SIRI is a strong and independent risk factor for adverse outcomes in patients with ACS undergoing percutaneous coronary intervention.Higher SIRI is associated with a more severe disease status.The SIRI could increase the prognostic value of the GRACE risk score.

Indexed as

Acute Coronary SyndromePercutaneous Coronary InterventionHumansPrognosisRisk AssessmentRisk FactorsSystemic Inflammatory Response SyndromeTreatment Outcomeacute coronary syndromecardiovascular outcomespercutaneous coronary interventionSystemic inflammatory response index

Identifiers

PMID35695557
PMCPMC9225721

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.