Evidence map›Paper›PMID 35696563›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Essential functions of mosquito ecdysone importers in development and reproduction.

Lewis V Hun, Naoki Okamoto, Eisuke Imura, Roilea Maxson, Riyan Bittar, Naoki Yamanaka

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Single-cell transcriptomics of theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Review
  5. Insect Sterols and Steroids.Advances in experimental medicine and biology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Lewis V HunDepartment of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, CA 92521.ORCID 0000-0002-8167-3455
Naoki OkamotoDepartment of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, CA 92521.ORCID 0000-0003-2371-5060
Eisuke ImuraDepartment of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, CA 92521.
Roilea MaxsonDepartment of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, CA 92521.ORCID 0000-0001-7795-6738
Riyan BittarDepartment of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, CA 92521.
Naoki YamanakaDepartment of Entomology, Institute for Integrative Genome Biology, University of California, Riverside, CA 92521.ORCID 0000-0002-6244-2686
University of California, Riverside · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
Membrane steroid hormone transporters in development and reproductionDP2GM132929 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI YAMANAKA, NAOKI · 2018 to 2018
$2.3M
NIGMS NIH HHS DP2 GM132929NIH HHS P40 OD010949NIH HHS P40 OD018537
6 · The paper itself

Abstract

The primary insect steroid hormone ecdysone requires a membrane transporter to enter its target cells. Although an organic anion-transporting polypeptide (OATP) named Ecdysone Importer (EcI) serves this role in the fruit fly

Indexed as

AedesEcdysoneInsect ProteinsOrganic Anion TransportersAnimalsDrosophilaDrosophila melanogasterFemaleVitellogenesisEcdysoneInsect ProteinsOrganic Anion TransportersAedes aegyptiDrosophila melanogasterecdysoneorganic anion-transporting polypeptide (OATP)vitellogenesis

Identifiers

PMID35696563
PMCPMC9231622
OpenAlexW4282576366

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.