Evidence map›Paper›PMID 35697698›Full record

ArticleScientific data2022

A database of anti-coronavirus peptides.

Qianyue Zhang, Xue Chen, Bowen Li, Chunying Lu, Shanshan Yang, Jinjin Long, Heng Chen, Jian Huang, Bifang He

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Mucosal immune response in biology, disease prevention and treatment.Signal transduction and targeted therapy · 2025
    Pooled it
  2. Article
  3. Review
  4. Human coronaviruses: activation and antagonism of innate immune responses.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. In Silico Discovery of Anticancer Peptides from Sanghuang.International journal of molecular sciences · 2022
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Qianyue ZhangMedical College, Guizhou University, Guiyang, 550025, China.
Xue ChenMedical College, Guizhou University, Guiyang, 550025, China.
Bowen LiMedical College, Guizhou University, Guiyang, 550025, China.
Chunying LuMedical College, Guizhou University, Guiyang, 550025, China.
Shanshan YangMedical College, Guizhou University, Guiyang, 550025, China.
Jinjin LongMedical College, Guizhou University, Guiyang, 550025, China.
Heng ChenMedical College, Guizhou University, Guiyang, 550025, China. hchen13@gzu.edu.cn.
Jian HuangSchool of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 611731, China. hj@uestc.edu.cn.
Bifang HeMedical College, Guizhou University, Guiyang, 550025, China. bfhe@gzu.edu.cn.
Guiyang Medical University · CNGuizhou University · CNUniversity of Electronic Science and Technology of China · CN

Funding

Guizhou University (GZU) (2018)54Guizhou University (GZU) (2018)55,[2020]5National Natural Science Foundation of China (National Science Foundation of China) 61901129National Natural Science Foundation of China (National Science Foundation of China) 61901130National Natural Science Foundation of China (National Science Foundation of China) 62071099
6 · The paper itself

Abstract

Since 2019, the novel coronavirus (SARS-COV-2) disease (COVID-19) has caused a worldwide epidemic. Anti-coronavirus peptides (ACovPs), a type of antimicrobial peptides (AMPs), have demonstrated excellent inhibitory effects on coronaviruses. However, state-of-the-art AMP databases contain only a small number of ACovPs. Additionally, the fields of these databases are not uniform, and the units or evaluation standards of the same field are inconsistent. Most of these databases have not included the target domains of ACovPs and description of in vitro and in vivo assays to measure the inhibitory effects of ACovPs. Here, we present a database focused on ACovPs (ACovPepDB), which contains comprehensive and precise ACovPs information of 518 entries with 214 unique ACovPs manually collected from public databases and published peer-reviewed articles. We believe that ACovPepDB is of great significance for facilitating the development of new peptides and improving treatment for coronavirus infection. The database will become a portal for ACovPs and guide and help researchers perform further studies. The ACovPepDB is available at http://i.uestc.edu.cn/ACovPepDB/ .

Indexed as

Antiviral AgentsCOVID-19 Drug TreatmentSARS-CoV-2Databases, ChemicalHumansPeptidesAntiviral AgentsPeptides

Identifiers

PMID35697698
PMCPMC9192597
OpenAlexW4282826631

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.