Evidence map›Paper›PMID 35697882›Full record

ArticleMikrochimica acta2022

Magnetic supercluster particles for highly sensitive magnetic biosensing of proteins.

Songeun Kim, Junyoung Kim, Jisoo Im, Minah Kim, Taehyeong Kim, Shan X Wang, Dokyoon Kim, Jung-Rok Lee

Abstract read
In one paragraph

Article in Mikrochimica acta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Fine-Tuning the Superparamagnetic Properties of FeO@FeACS applied materials & interfaces · 2025
    Article
  6. Article
  7. Article
  8. Article
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Songeun KimDivision of Mechanical and Biomedical Engineering, Ewha Womans University, Seoul, 03760, Republic of Korea.
Junyoung KimDepartment of Bionano Engineering and Bionanotechnology, Hanyang University, Ansan, 15588, Republic of Korea.
Jisoo ImDivision of Mechanical and Biomedical Engineering, Ewha Womans University, Seoul, 03760, Republic of Korea.
Minah KimDepartment of Bionano Engineering and Bionanotechnology, Hanyang University, Ansan, 15588, Republic of Korea.
Taehyeong KimDepartment of Bionano Engineering and Bionanotechnology, Hanyang University, Ansan, 15588, Republic of Korea.
Shan X WangDepartment of Materials Science and Engineering, Stanford University, Stanford, CA, 94305, USA.
Dokyoon KimDepartment of Bionano Engineering and Bionanotechnology, Hanyang University, Ansan, 15588, Republic of Korea. kimdk@hanyang.ac.kr.
Jung-Rok LeeDivision of Mechanical and Biomedical Engineering, Ewha Womans University, Seoul, 03760, Republic of Korea. jungrok@ewha.ac.kr.ORCID http://orcid.org/0000-0002-3518-3965

Funding

Rapid and affordable magneto-nanosensors for ctDNA-guided lung cancer managementR01CA257843 · NCI · STANFORD UNIVERSITY · PI WANG, SHAN X. · 2021 to 2024
$2.2M
National Research Foundation of Korea NRF-2018R1A6A1A03024231National Research Foundation of Korea NRF-2018R1D1A1B07050979National Research Foundation of Korea NRF-2019M3C1B8090804National Research Foundation of Korea NRF-2020R1C1C1005416National Research Foundation of Korea NRF-2022R1A2C1003527NCI NIH HHS R01 CA257843NCI NIH HHS R01CA25784301NIH HHS R01CA25784301
6 · The paper itself

Abstract

A strategy is reported to improve the detection limits of current giant magnetoresistance (GMR) biosensors by augmenting the effective magnetic moment that the magnetic tags on the biosensors can exert. Magnetic supercluster particles (MSPs), each of which consists of ~ 1000 superparamagnetic cores, are prepared by a wet-chemical technique and are utilized to improve the limit of detection of GMR biosensors down to 17.6 zmol for biotin as a target molecule. This value is more than four orders of magnitude lower than that of the conventional colorimetric assay performed using the same set of reagents except for the signal transducer. The applicability of MSPs in immunoassay is further demonstrated by simultaneously detecting vascular endothelial growth factor (VEGF) and C-reactive protein (CRP) in a duplex assay format. MSPs outperform commercially available magnetic nanoparticles in terms of signal intensity and detection limit.

Indexed as

Biosensing TechniquesVascular Endothelial Growth Factor AImmunoassayMagnetic PhenomenaMagneticsVascular Endothelial Growth Factor ABiosensorsGiant magnetoresistanceImmunoassayMagnetic nanoparticlesSupercluster particles

Identifiers

PMID35697882
PMCPMC9192248

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.