Evidence map›Paper›PMID 35697905›Full record

ArticleScientific reports2022

Prevalence and factors associated with overweight, obesity, and hypertension in a large clinical sample of adults with autism spectrum disorder.

Robyn P Thom, Michelle L Palumbo, Christopher J Keary, Jacob M Hooker, Christopher J McDougle, Caitlin T Ravichandran

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Article
  6. Genetic Testing History in Adults With Autism Spectrum Disorder.Journal of autism and developmental disorders · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Health conditions in autism: Defining the trajectory from adolescence to early adulthood.Autism research : official journal of the International Society for Autism Research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Robyn P ThomLurie Center for Autism, 1 Maguire Road, Lexington, MA, 02421, USA. rthom@mgh.harvard.edu.
Michelle L PalumboLurie Center for Autism, 1 Maguire Road, Lexington, MA, 02421, USA.
Christopher J KearyLurie Center for Autism, 1 Maguire Road, Lexington, MA, 02421, USA.
Jacob M HookerLurie Center for Autism, 1 Maguire Road, Lexington, MA, 02421, USA.
Christopher J McDougleLurie Center for Autism, 1 Maguire Road, Lexington, MA, 02421, USA.
Caitlin T RavichandranLurie Center for Autism, 1 Maguire Road, Lexington, MA, 02421, USA.
Harvard University · USMassachusetts General Hospital · USLemuel Shattuck Hospital · USMcLean Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adults with autism spectrum disorder (ASD) are at risk for excess bodyweight and hypertension, yet the prevalence of and clinical predictors for these health conditions remain unknown. The objective of this study was to assess the prevalence of overweight, obesity, and hypertension in a large clinical sample of adults with a confirmed diagnosis of ASD and to examine potential clinical predictors. This retrospective chart review study included adult subjects (≥ 20 years) with ASD who had been seen within the past 5 years at a multidisciplinary developmental disorders clinic. Data collected from the electronic health record included age, sex, race and ethnicity, cognitive ability, language ability, body mass index (BMI), hypertension, and use of second generation antipsychotic medications (SGAs). Of 622 adults with a confirmed diagnosis of ASD potentially eligible for the study, 483 (78%) had one or more notes in their records from the past 5 years. Those with recent notes were 23% female, 89% White, and had a mean (SD) age of 28.1 (7.1) years. Overall prevalence estimates for adults represented by this predominantly male, White, and young clinical sample were 28% (95% CI 24%, 32%) for overweight (BMI 25-29.9 kg/m

Indexed as

Autism Spectrum DisorderHypertensionIntellectual DisabilityAdultFemaleHumansMaleObesityOverweightPrevalenceRetrospective Studies

Identifiers

PMID35697905
PMCPMC9192602
OpenAlexW4282598389

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.