Evidence map›Paper›PMID 35698663›Full record

ArticleThe application of clinical genetics2022

Evaluating the Association Between Genetic Polymorphisms Related to Homocysteine Metabolism and Unexplained Recurrent Pregnancy Loss in Women.

Nhat Nguyen Ngoc, My Tran Ngoc Thao, Sang Trieu Tien, Son Vu Tung, Hoang Le, Hung Ho Sy, Tung Nguyen Thanh, Son Trinh The

Open access · goldAbstract read
In one paragraph

Article in The application of clinical genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Nhat Nguyen NgocMilitary Institute of Clinical Embryology and Histology, Vietnam Military Medical University, Hanoi, 12108, Vietnam.ORCID 0000-0003-3378-9290
My Tran Ngoc ThaoDépartement de formation Biologie moléculaire et cellulaire, Sorbonne University, Paris, 75006, France.ORCID 0000-0001-5237-4723
Sang Trieu TienDepartment of Biology and Genetics, Vietnam Military Medical University, Hanoi, 12108, Vietnam.ORCID 0000-0001-6835-0718
Son Vu TungDepartment of Epidemiology, Vietnam Military Medical University, Hanoi, 12108, Vietnam.
Hoang LeIVFTA, Tam Anh General Hospital, Hanoi, 100000, Vietnam.
Hung Ho SyDepartment of Obstetrics and Gynecology, Hanoi Medical University, Hanoi, 100000, Vietnam.ORCID 0000-0002-0497-3104
Tung Nguyen ThanhMilitary Institute of Clinical Embryology and Histology, Vietnam Military Medical University, Hanoi, 12108, Vietnam.
Son Trinh TheMilitary Institute of Clinical Embryology and Histology, Vietnam Military Medical University, Hanoi, 12108, Vietnam.ORCID 0000-0002-3807-9645
Vietnam Military Medical University · VNHanoi Medical University · VNKhanh Hoa General Hospital · VNSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the relationship between unexplained recurrent pregnancy loss (URPL) and polymorphisms of homocysteine metabolism-related genes in women. Materials and Methods: A case-control study included 90 women with two or more consecutive unexplained pregnancy losses and 92 controlled women without miscarriage history; the female participants were in the age category of 18-35 years. The high-resolution melting technique was used to detect the single-nucleotide variants related to homocysteine metabolism disorder, namely Results: The Conclusion: The

Indexed as

homocysteineMTHFR A1298CMTHFR C677TMTR A2756GMTRR A66Gunexplained recurrent pregnancy loss

Identifiers

PMID35698663
PMCPMC9188402
OpenAlexW4281659692

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.