ArticleAmerican journal of respiratory and critical care medicine2022
Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
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Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.
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0cells of the map it votes in
107citing papers in PubMed
27.7field-weighted citation impact, top 1% of its field
What it found
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Who cites it
107 citing papers in PubMed, 194 citations in OpenAlex.
- Pharmacokinetics, Safety Profile, and Tolerability of MN-08 Tablets after Single and Multiple Ascending Doses in Healthy Chinese Volunteers.Clinical drug investigation · 2026Trial
- Effect of inferior caval valve implantation on circulating immune cells and inflammatory mediators in severe tricuspid regurgitation.BMC cardiovascular disorders · 2024Trial
- PET Imaging in Pulmonary Hypertension.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Beyond the Heart-Lung Axis: A Review of the Crosstalk Between the Hemodynamic, Neurohormonal, and Immune Systems in Pulmonary Hypertension.Comprehensive physiology · 2026Review
- Mitophagy and Noncoding RNA Regulation in Type 2 Diabetes Mellitus: Molecular Mechanisms, Tissue-Specific Evidence and Translational Perspective.Biomedicines · 2026Review
- Autophagy-Targeted Vascular Remodeling in Pulmonary Arterial Hypertension: Molecular Mechanisms and Therapeutic Perspectives.Journal of cardiovascular development and disease · 2026Review
- Ventricular arrhythmogenesis in pulmonary hypertension: From right ventricular remodeling to clinical implications.Physiological reports · 2026Review
- The NLRP3 inflammasome as a dynamic context-dependent regulator: mechanisms, disease progression, and therapeutic implications.Journal of translational medicine · 2026Review
- Pulmonary Hypertension Molecular Switch: HIF Signaling Pathway.Pulmonary circulation · 2026Review
- Cardiometabolic reprogramming in pulmonary arterial hypertension: Implications for right ventricular dysfunction and therapeutic strategies.Chinese herbal medicines · 2026Review
- The NLRP3 Inflammasome Increases Pulmonary Vascular Remodeling in Experimental Pulmonary Arterial Hypertension.Pulmonary circulation · 2026Article
- The Interplay of Programmed Cell Death Networks in Cardiovascular Diseases: Mechanisms and Therapeutic Opportunities.Reviews in cardiovascular medicine · 2026Review
- Review
- Endothelial-to-Mesenchymal Transition Mechanisms in Vascular Remodeling of Pulmonary Hypertension.International journal of molecular sciences · 2026Review
- Targeting the Hippo pathway in pulmonary arterial hypertension: emerging pharmacological strategies.Journal of hypertension · 2026Review
- Targeting REV-ERBα/BNIP3 axis attenuates pulmonary arterial hypertension by repressing mitophagy in mice.Nature communications · 2026Article
- Advances in the pathogenesis and clinical management of pulmonary hypertension.Medical review (2021) · 2026Review
- Activation of α7nAChR prevents maladaptive right ventricular remodeling via inhibiting the recruitment of CCR2Respiratory research · 2026Article
- Oxidized mtDNA Contributes to Pulmonary Inflammation and Fibrosis in Bleomycin-Induced Lung Injury.MedComm · 2026Article
- Study of the Mechanism by Which Shenfu Injection Regulates Cardiomyocyte Hypertrophy Based on Dopamine Receptor D2-Mediated Mitochondrial Fission.Anatolian journal of cardiology · 2026Article
47 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 3 countries.
Ruaa Al-QazaziDepartment of Medicine.ORCID 0000-0003-0983-9745
Patricia D A LimaDepartment of Medicine.ORCID 0000-0002-6456-2470
Sasha Z PriscoCardiovascular Division, Lillehei Heart Institute, University of Minnesota Medical School, Minneapolis, Minnesota.
Francois PotusDepartment of Medicine.
Asish DasguptaDepartment of Medicine.
Kuang-Hueih ChenDepartment of Medicine.
Lian TianDepartment of Medicine.
Rachel E T BentleyDepartment of Medicine.
Jeff MewburnDepartment of Medicine.
Ashley Y MartinDepartment of Medicine.
Danchen WuDepartment of Medicine.
Oliver JonesQueen's Cardiopulmonary Unit, and.
Donald H MauriceDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Sebastien BonnetPulmonary Hypertension Research Group, Institut Universitaire de Cardiologie et de Pneumologie de Québec Research Center, Laval University, Quebec City, Quebec, Canada; and.ORCID 0000-0001-5753-1900
Steeve ProvencherPulmonary Hypertension Research Group, Institut Universitaire de Cardiologie et de Pneumologie de Québec Research Center, Laval University, Quebec City, Quebec, Canada; and.
Kurt W PrinsCardiovascular Division, Lillehei Heart Institute, University of Minnesota Medical School, Minneapolis, Minnesota.ORCID 0000-0002-0364-6742
Stephen L ArcherDepartment of Medicine.ORCID 0000-0003-1106-3202
Queen's University · CAInstitut universitaire de cardiologie et de pneumologie de Québec · CAUniversity of Minnesota · USUniversity of Strathclyde · GB
Funding
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9MGP130 Antagonism in Porcine RV Pressure OverloadR01HL162927 · NHLBI · UNIVERSITY OF MINNESOTA · PI Kurt W Prins · 2022 to 2026
$3.3MO2 sensing in the human and rabbit ductus arteriosus.R01HL071115 · NHLBI · UNIVERSITY OF CHICAGO · PI ARCHER, STEPHEN L · 2004 to 2015
$3.1MMulti-scale Investigation of Sex Differences in Right Ventricular Function via Estrogen-Microtubule InteractionsR01HL158795 · NHLBI · UNIVERSITY OF MINNESOTA · PI Kurt W Prins · 2022 to 2026
$2.8MTraining Program in Cardiac InnovationT32HL144472 · NHLBI · UNIVERSITY OF MINNESOTA · PI Peter A Crawford, SAMUEL C DUDLEY · 2019 to 2026
$2.6MThe Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial HypertensionR01HL113003 · NHLBI · QUEEN'S UNIVERSITY AT KINGSTON · PI ARCHER, STEPHEN L · 2013 to 2016
$1.1MMechanisms of Junctophilin-2 Misregulation that contribute to right ventricular dysfunction in pulmonary arterial hypertensionK08HL140100 · NHLBI · UNIVERSITY OF MINNESOTA · PI PRINS, KURT W · 2018 to 2022
$785kInfluences of sex hormones on the microtubule cytoskeleton in right ventricular dysfunctionF32HL154533 · NHLBI · UNIVERSITY OF MINNESOTA · PI PRISCO, SASHA ZHENG · 2021 to 2021
$73kNational Institutes of Health (NIH) NIH T32 HL144472NCATS NIH HHS UL1 TR002494NHLBI NIH HHS F32 HL154533NHLBI NIH HHS K08 HL140100NHLBI NIH HHS R01 HL071115NHLBI NIH HHS R01 HL113003NHLBI NIH HHS R01 HL158795NHLBI NIH HHS R01 HL162927NHLBI NIH HHS T32 HL144472NIH HHS NIH R01HL071115NIH HHS NIH R01HL113003
Abstract
PubMed holds no abstract for this paper.
Indexed as
Heart FailureHypertension, PulmonaryPulmonary Arterial HypertensionVentricular Dysfunction, RightAnimalsAtrial Natriuretic FactorCytokine Receptor gp130Disease Models, AnimalFamilial Primary Pulmonary HypertensionFibrosisHeart VentriclesHypertrophy, Right VentricularInflammasomesMacrophage ActivationMacrophagesMonocrotalineAtrial Natriuretic FactorCytokine Receptor gp130InflammasomesMonocrotalineNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, ratCCR2IL-1βMCC950mitochondrial fissionSC-144
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.