Evidence map›Paper›PMID 35700364›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Meeting a threat of the Anthropocene: Taste avoidance of metal ions by

Shuke Xiao, Lisa S Baik, Xueying Shang, John R Carlson

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Review
  3. Insects · 2026
    Article
  4. Gustatory avoidance of fatty acids byProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shuke XiaoDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511.
Lisa S BaikDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511.ORCID 0000-0001-8184-2039
Xueying ShangDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511.
John R CarlsonDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06511.ORCID 0000-0002-0244-5180
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
ANALYSIS OF ODORANT RECEPTOR GENESR01DC004729 · NIDCD · YALE UNIVERSITY · PI John R Carlson · 2001 to 2026
$9.2M
GENETIC AND MOLECULAR ANALYSIS OF OLFACTIONR01DC002174 · NIDCD · YALE UNIVERSITY · PI CARLSON, JOHN R · 1994 to 2024
$8.0M
Analysis of a large family of taste receptorsR01DC011697 · NIDCD · YALE UNIVERSITY · PI John R Carlson · 2011 to 2026
$5.5M
Taste perception in the disease vector mosquito Aedes albopictusF32DC019250 · NIDCD · YALE UNIVERSITY · PI BAIK, LISA SOYEON · 2020 to 2023
$204k
NCATS NIH HHS UL1 TR001863NIDCD NIH HHS F32 DC019250NIDCD NIH HHS R01 DC002174NIDCD NIH HHS R01 DC004729NIDCD NIH HHS R01 DC011697
6 · The paper itself

Abstract

The Anthropocene Epoch poses a critical challenge for organisms: they must cope with new threats at a rapid rate. These threats include toxic chemical compounds released into the environment by human activities. Here, we examine elevated concentrations of heavy metal ions as an example of anthropogenic stressors. We find that the fruit fly

Indexed as

Anthropogenic EffectsDrosophila melanogasterEnvironmental ExposureEscape ReactionMetals, HeavyTasteTaste PerceptionAedesAnimalsAvoidance LearningCationsDrosophila ProteinsHumansReceptors, Ionotropic GlutamateCationsDrosophila ProteinsMetals, HeavyReceptors, Ionotropic GlutamateAnthropoceneDrosophilametaltaste

Identifiers

PMID35700364
PMCPMC9231609
OpenAlexW4282914651

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.