Evidence map›Paper›PMID 35704134›Full record

ArticleChild psychiatry and human development2024

Brain Anatomy in Boys with Conduct Disorder: Differences Among Aggression Subtypes.

Yali Jiang, Yidian Gao, Daifeng Dong, Xiaoqiang Sun, Weijun Situ, Shuqiao Yao

Abstract read
PubMed Publisher
In one paragraph

Article in Child psychiatry and human development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Behavioral disorders in multiple sclerosis: a comprehensive review.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  3. Article
  4. Association between lower-level of environmental lead exposure and reactive and proactive aggression in youth: Sex differences.Journal of environmental science and health. Part C, Toxicology and carcinogenesis · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yali JiangMedical Psychological Center, the Second Xiangya Hospital of Central South University, No. 139, Middle Renmin Road, 410011, Changsha, Hunan, People's Republic of China.
Yidian GaoCenter for Studies of Psychological Application, South China Normal University, Guangzhou, China.
Daifeng DongGuangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, Guangzhou, China.
Xiaoqiang SunGuangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, Guangzhou, China.
Weijun SituDepartment of Radiology, the Second Xiangya Hospital, Central South University, 139, Middle Renmin Road, 410011, Changsha, Hunan, People's Republic of China. stwj74@sina.com.
Shuqiao YaoMedical Psychological Center, the Second Xiangya Hospital of Central South University, No. 139, Middle Renmin Road, 410011, Changsha, Hunan, People's Republic of China. shuqiaoyao@csu.edu.cn.
South China Normal University · CNCentral South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

Guangdong Basic and Applied Basic Research Foundation 2021A1515011359Natural Science Foundation of China 81471384
6 · The paper itself

Abstract

Aggression is a core feature of conduct disorder (CD), but the motivation, execution of aggression may vary. A deeper understanding of the neural substrates of aggressive behaviours is critical for effective clinical intervention. Seventy-six Boys with CD (50 with impulsive aggression (I-CD) and 26 with premeditated aggression (P-CD)) and 69 healthy controls (HCs) underwent a structural MRI scan and behavioural assessments. Whole-brain analyses revealed that, compared to HCs, the I-CD group showed significant cortical thinning in the right frontal cortex, while the P-CD group demonstrated significant folding deficits in the bilateral superior parietal cortex. Both types of aggression negatively correlated with the left amygdala volume, albeit in different ways. The present results demonstrated that the complex nature of aggression relies on differentiated anatomical substrates, highlighting the importance of exploring differential circuit-targeted interventions for CD patients.

Indexed as

Conduct DisorderAggressionBrainHumansMagnetic Resonance ImagingMaleAdolescentsConduct disorderImpulsive aggressionPremeditated aggressionsMRI

Identifiers

PMID35704134
OpenAlexW4282964932

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.