Evidence map›Paper›PMID 35704961›Full record

ArticleJournal of the neurological sciences2022

Relationship between parental history of dementia, motor-cognitive and executive function performance in African American women.

Allison A Bay, Nicole Schindler, Whitney Wharton, Hayley Silverstein, Liang Ni, Todd A Prusin, Madeleine E Hackney

Open access · greenAbstract read
In one paragraph

Article in Journal of the neurological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Allison A BayEmory University School of Medicine, Department of Medicine, Division of Geriatrics & Gerontology, 100 Woodruff Circle, Atlanta, GA 30322, United States of America.
Nicole SchindlerEmory College of Arts and Sciences, 550 Asbury Circle, Atlanta, GA 30322, United States of America.
Whitney WhartonEmory University School of Nursing, 1520 Clifton Rd., Atlanta, GA 30322, United States of America.
Hayley SilversteinAtlanta VA Center for Visual & Neurocognitive Rehabilitation, 1670 Clairmont Rd, Decatur, GA 30033, United States of America; Emory University School of Medicine, Department of Medicine, Division of Geriatrics & Gerontology, 100 Woodruff Circle, Atlanta, GA 30322, United States of America.
Liang NiEmory University School of Medicine, Department of Medicine, Division of Geriatrics & Gerontology, 100 Woodruff Circle, Atlanta, GA 30322, United States of America.
Todd A PrusinEmory University School of Medicine, Department of Medicine, Division of Geriatrics & Gerontology, 100 Woodruff Circle, Atlanta, GA 30322, United States of America.
Madeleine E HackneyEmory University School of Nursing, 1520 Clifton Rd., Atlanta, GA 30322, United States of America; Atlanta VA Center for Visual & Neurocognitive Rehabilitation, 1670 Clairmont Rd, Decatur, GA 30033, United States of America; Emory University School of Medicine, Department of Medicine, Division of Geriatrics & Gerontology, 100 Woodruff Circle, Atlanta, GA 30322, United States of America; Emory University School of Medicine, Department of Rehabilitation Medicine, 1841 Clifton Rd. NE, Atlanta, GA 30329, United States of America; Birmingham/Atlanta VA Geriatric Research Education and Clinical Center, 3101 Clairmont Rd. NE, Brookhaven, GA 30329, United States of America. Electronic address: mehackn@emory.edu.
Emory University · USGeriatric Research Education and Clinical Center · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalKL2TR000455 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$2.9M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalTL1TR000456 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$1.2M
Optimizing motor training in Parkinson disease through neural mechanismsIK2RX000870 · VA · VETERANS HEALTH ADMINISTRATION · PI HACKNEY, MADELEINE EVE · 2015 to 2018
–
NCATS NIH HHS KL2 TR000455NCATS NIH HHS TL1 TR000456NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR002378NCRR NIH HHS UL1 RR025008RRD VA IK2 RX000870
6 · The paper itself

Abstract

People with parental history (PH) of Alzheimer's Disease (AD) and Alzheimer's Disease and related dementias (ADRD) are themselves at risk of developing dementia. ADRD are more prevalent in African Americans and women. A decline in executive function and motor-cognitive integration can cause an impaired performance of functional skills. The monitoring of cognitive and psychosocial function in individuals with a PH of ADRD is important for implementing interventions to delay or prevent ADRD diagnosis. This study compared 58 African American women (M age = 63.2 ± 7.2 years) with PH of ADRD (n = 34) versus without PH (NPH; n = 24) on the performance of motor-cognitive and executive function tasks, and mental and physical quality of life (QOL) using point biserial correlations and linear regression. Linear regression revealed no difference between participants with and without PH on motor-cognitive tests. However, compared to participants with NPH, participants with PH of ADRD performed significantly worse on the DKEFS (Delis Kaplan Executive Function System) Tower Test (PH: M = 9.9 ± 2.0; NPH: M = 11.5 ± 4.3; p = 0.046), had poorer mental QOL (PH: M = 46.8 ± 10.7; NPH: M = 52.8 ± 7.8 l; p = 0.007); and physical QOL (PH: M = 40.9 ± 9.3; NPH: M = 44.7 ± 8.6; p = 0.023). African American women at risk for ADRD may exhibit deficiencies in executive function and physical and mental quality of life before memory deficits meet the criterion for ADRD diagnosis. Motor-Cognitive tasks may be preserved. Executive function and mental and physical health-related QOL may be important targets for identifying individuals at increased risk for ADRD and developing appropriate rehabilitative interventions.

Indexed as

Alzheimer DiseaseDementiaAgedBlack or African AmericanCognitionExecutive FunctionFemaleHumansMiddle AgedParentsQuality of LifeAfrican AmericanDementiaExecutive functionFamily historyFemaleQuality of life

Identifiers

PMID35704961
PMCPMC9762457
OpenAlexW4283017391

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.