Evidence map›Paper›PMID 35708754›Full record

ArticleJMIR medical informatics2022

Predicting Risk of Hypoglycemia in Patients With Type 2 Diabetes by Electronic Health Record-Based Machine Learning: Development and Validation.

Hao Yang, Jiaxi Li, Siru Liu, Xiaoling Yang, Jialin Liu

Open access · goldAbstract read
In one paragraph

Article in JMIR medical informatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
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  10. Artificial Intelligence to Diagnose Complications of Diabetes.Journal of diabetes science and technology · 2025
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  12. Comparative Analysis of Fusion Strategies for Imaging and Non-imaging Data - Use-case of Hospital Discharge Prediction.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Hao Yang *Information Center, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-3505-9403
Jiaxi Li *Department of Clinical Laboratory Medicine, Jinniu Maternity and Child Health Hospital of Chengdu, Chengdu, China.ORCID https://orcid.org/0000-0002-9820-8461
Siru LiuDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.ORCID https://orcid.org/0000-0002-5003-5354
Xiaoling YangWest China School of Nursing, Endocrinology and Metabolism Department, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0003-2943-880X
Jialin LiuInformation Center, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-1369-4625
Sichuan University · CNMaternal and Child Health Hospital of Sichuan Province · CNVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypoglycemia is a common adverse event in the treatment of diabetes. To efficiently cope with hypoglycemia, effective hypoglycemia prediction models need to be developed.

objectiveThe aim of this study was to develop and validate machine learning models to predict the risk of hypoglycemia in adult patients with type 2 diabetes.

methodsWe used the electronic health records of all adult patients with type 2 diabetes admitted to West China Hospital between November 2019 and December 2021. The prediction model was developed based on XGBoost and natural language processing. F1 score, area under the receiver operating characteristic curve (AUC), and decision curve analysis (DCA) were used as the main criteria to evaluate model performance.

resultsWe included 29,843 patients with type 2 diabetes, of whom 2804 patients (9.4%) developed hypoglycemia. In this study, the embedding machine learning model (XGBoost3) showed the best performance among all the models. The AUC and the accuracy of XGBoost are 0.82 and 0.93, respectively. The XGboost3 was also superior to other models in DCA.

conclusionsThe Paragraph Vector-Distributed Memory model can effectively extract features and improve the performance of the XGBoost model, which can then effectively predict hypoglycemia in patients with type 2 diabetes.

Indexed as

diabetesEHRelectronic health recordhypoglycemialearningmachine learning modelnatural language processingtype 2 diabetesXGBoost

Identifiers

PMID35708754
PMCPMC9247813
OpenAlexW4283008433

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.