Evidence map›Paper›PMID 35710732›Full record

ArticleCommunications biology2022

Integrative multi-omic analysis identifies genetically influenced DNA methylation biomarkers for breast and prostate cancers.

Anita Sathyanarayanan, Hamzeh M Tanha, Divya Mehta, Dale R Nyholt

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anita SathyanarayananQueensland University of Technology, Centre for Genomics and Personalised Health, Faculty of Health, Kelvin Grove, QLD, Australia. a.sathyanarayanan@qut.edu.au.ORCID http://orcid.org/0000-0001-8385-5618
Hamzeh M TanhaQueensland University of Technology, Centre for Genomics and Personalised Health, Faculty of Health, Kelvin Grove, QLD, Australia.ORCID http://orcid.org/0000-0003-0818-3481
Divya MehtaQueensland University of Technology, Centre for Genomics and Personalised Health, Faculty of Health, Kelvin Grove, QLD, Australia.ORCID http://orcid.org/0000-0002-7359-348X
Dale R NyholtQueensland University of Technology, Centre for Genomics and Personalised Health, Faculty of Health, Kelvin Grove, QLD, Australia. d.nyholt@qut.edu.au.ORCID http://orcid.org/0000-0001-7159-3040
Queensland University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant DNA methylation has emerged as a hallmark in several cancers and contributes to risk, oncogenesis, progression, and prognosis. In this study, we performed imputation-based and conventional methylome-wide association analyses for breast cancer (BrCa) and prostate cancer (PrCa). The imputation-based approach identified DNA methylation at cytosine-phosphate-guanine sites (CpGs) associated with BrCa and PrCa risk utilising genome-wide association summary statistics (N

Indexed as

Breast NeoplasmsProstatic NeoplasmsCpG IslandsDNA MethylationGenetic MarkersGenome-Wide Association StudyHumansMaleGenetic Markers

Identifiers

PMID35710732
PMCPMC9203749
OpenAlexW4282966799

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.