SynthesisFrontiers in nutrition2022
Egg and Dietary Cholesterol Intake and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.
Synthesis in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- An Analysis of the Nutritional Value of Diets Generated by Large Language Models Under Average User Conditions-3(LM)Diet Study.Nutrients · 2026Article
- Dietary cholesterol intake and egg consumption in relation to all-cause and cardiovascular mortality after stroke.Scientific reports · 2025Article
- Egg Consumption and Mortality: A Prospective Cohort Study of Australian Community-Dwelling Older Adults.Nutrients · 2025Article
- Redefining Protein Quality: Integrating Health Outcomes and Environmental Impacts in the Plant-Animal Protein Debate.Foods (Basel, Switzerland) · 2024Article
- A multicriteria analysis of meat and milk alternatives from nutritional, health, environmental, and cost perspectives.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Empirically derived dietary patterns are associated with major adverse cardiovascular events, all-cause mortality, and congestive cardiac failure in older men: The Concord Health and Ageing in Men Project.The journal of nutrition, health & aging · 2024Article
- Meat-egg-dairy consumption and depressive symptoms among Chinese older adults: exploring rural/urban and gender disparities.Frontiers in psychiatry · 2024Article
- Diet Quality and Mortality among Chinese Adults: Findings from the China Health and Nutrition Survey.Nutrients · 2023Article
- Eggs: Healthy or Risky? A Review of Evidence from High Quality Studies on Hen's Eggs.Nutrients · 2023Review
- The Global Association between Egg Intake and the Incidence and Mortality of Ischemic Heart Disease-An Ecological Study.International journal of environmental research and public health · 2023Article
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This systematic review and meta-analysis of prospective cohort studies examined the associations between egg and dietary cholesterol intake and the risk of mortality from all causes, including cardiovascular disease (CVD) and cancer. Methods: We searched PubMed, Scopus, ISI Web of Knowledge, and Google Scholar until April 2021, as well as references to the relevant articles retrieved. Random-effects models were used to calculate summary relative risk (RR) and 95% confidence intervals (CIs) for the highest vs. lowest categories of egg and dietary cholesterol intake. Also, linear and non-linear dose-response analyses were conducted to examine the dose-response relationships. Results: We included 55 studies, comprising data from 2,772,486 individuals with 228,425, 71,745, and 67,211 cases of all-cause, CVD, and cancer mortality, respectively. Intake of each additional egg per day was associated with a 7% higher risk of all-cause (1.07, 95% CI: 1.02-1.12, I Conclusions and Relevance: High-dietary intake of eggs and cholesterol was associated with all-cause and cancer mortality. Little evidence for elevated risks was seen for intakes below 0.5 egg/day or 250 mg/day of dietary cholesterol. Our findings should be considered with caution because of small risk estimates and moderate between-study heterogeneity. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=252564, PROSPERO, identifier: CRD42021252564.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.