ArticleFrontiers in pain research (Lausanne, Switzerland)2022
Home-Based EEG Neurofeedback Intervention for the Management of Chronic Pain.
Article in Frontiers in pain research (Lausanne, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04418362 (Axon - Brain Train for Pain - A Home-based Neurofeedback Intervention to Treat the Primary and Secondary Symptoms of Chronic Pain), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Axon - Brain Train for Pain - A Home-based Neurofeedback Intervention to Treat the Primary and Secondary Symptoms of Chronic Pain
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Ethical challenges in EEG neurofeedback: a systematic review of gaps, risks, and responsibilities.BMC medical ethics · 2026Pooled it
- Neuroimaging Insights into the Public Health Burden of Neuropsychiatric Disorders: A Systematic Review of Electroencephalography-Based Cognitive Biomarkers.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Neurofeedback for functional neurological disorders: future directions for research and clinical practice.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- Automated Anxiety Detection System Integrating a Brain-Computer Interface for Neurofeedback Applications.Sensors (Basel, Switzerland) · 2026Article
- EEG-Based Cortical Alterations in Patients Following Total Hip and Knee Arthroplasty Due to Osteoarthritis: Pre- and Post-Operative Assessment.Brain and behavior · 2026Article
- Closed-loop EEG-based neurofeedback and brain-computer interface interventions for mental health: a review.Frontiers in neuroscience · 2026Review
- A home-based EEG neurofeedback treatment for chronic neuropathic pain-a pilot study.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Feasibility and Safety of a Home-based Electroencephalogram Neurofeedback Intervention to Reduce Chronic Neuropathic Pain: A Cohort Clinical Trial.Archives of rehabilitation research and clinical translation · 2024Article
- A Scoping Review of the Effect of EEG Neurofeedback on Pain Complaints in Adults with Chronic Pain.Journal of clinical medicine · 2024Article
- Remote Wearable Neuroimaging Devices for Health Monitoring and Neurophenotyping: A Scoping Review.Biomimetics (Basel, Switzerland) · 2024Article
- Electroencephalography-based biological and functional characteristics of spinal cord injury patients with neuropathic pain and numbness.Frontiers in neuroscience · 2024Article
- Home-based brain-computer interface attention training program for attention deficit hyperactivity disorder: a feasibility trial.Child and adolescent psychiatry and mental health · 2023Article
- Assessment of the capacity to modulate brain signals in a home-based SMR neurofeedback training setting.Frontiers in human neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic pain and associated symptoms often cause significant disability and reduced quality of life (QoL). Neurofeedback (NFB) as part of a Brain Computer Interface can help some patients manage chronic pain by normalising maladaptive brain activity measured with electroencephalography (EEG). Objectives: This study was designed to assess the efficacy and safety of a novel home-based NFB device for managing chronic pain by modifying specific EEG activity. Methods: A prospective, single-arm, proof-of-concept study was conducted between June 2020 and March 2021 among adults with chronic pain (registered with ClinicalTrials.gov NCT04418362). Axon EEG NFB systems for home use were provided to each, and 32-48 NFB training sessions were completed by the participants over 8-weeks. The primary outcome was self-reported pain. Assessment of central sensitisation, sleep quality, affective symptoms, change in QoL, adverse events during use and EEG correlations with symptoms were secondary outcomes. Results: Sixteen participants were enrolled. Eleven reported pain relief following NFB training, eight reporting clinically significant improvements. Central sensitisation symptoms improved by a third ( Conclusions: Home-based NFB training is well-tolerated and may provide relief for sufferers of chronic pain and its associated symptoms. Summary:
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.