ReviewPediatric nephrology (Berlin, Germany)2022
Management of the congenital solitary kidney: consensus recommendations of the Italian Society of Pediatric Nephrology.
Review in Pediatric nephrology (Berlin, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- A Systematic Review for Guidelines: Sports and High-Grade Kidney Injuries in Children With Solitary Kidneys.Acta paediatrica (Oslo, Norway : 1992) · 2025Pooled it
- Airbag Vests in Equestrian Sports: Is Use Associated with Harm?Annals of biomedical engineering · 2024Pooled it
- Early diagnosis and intervention in congenital lower urinary tract obstruction: time to revise our approach?Pediatric nephrology (Berlin, Germany) · 2026Review
- CAKUT: Current Understanding and Future Directions.Indian journal of pediatrics · 2026Article
- HNF1B nephropathy: for which congenital renal anomalies is genetic analysis advisable?Pediatric nephrology (Berlin, Germany) · 2026Article
- Genetics of CAKUT.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2026Article
- Abnormal parenchymal features in the contralateral kidney of patients with multicystic dysplastic kidney.Pediatric nephrology (Berlin, Germany) · 2026Article
- Posterior bladder-associated pelvic cystic lesion with histologic features consistent with mesenteric cyst in an infant with a functionally solitary kidney: a diagnostic uncertainty case report.Frontiers in pediatrics · 2026Article
- Kidney injury risk in congenital solitary functioning kidney: the role of nephron mass assessed by serum uromodulin and the rs4293393 T > C polymorphism.BMC research notes · 2025Article
- Early identification of CKD in patients with solitary functioning kidney.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Article
- Unilateral Renal Agenesis: Prenatal Diagnosis and Postnatal Issues.Diagnostics (Basel, Switzerland) · 2025Review
- Morbidity in children with major kidney anomalies: a European population-based study.European journal of pediatrics · 2025Article
- Risk factors for chronic kidney disease in Japanese infants with solitary functioning kidney.Clinical and experimental nephrology · 2025Article
- Clinical outcomes and risk factors in pediatric patients with solitary functioning kidney: a comparative analysis of congenital and acquired etiologies.Frontiers in pediatrics · 2025Article
- Risks of Renal Anomalies and Urinary Tract Infections in Neonates With Single Umbilical Artery.Cureus · 2024Article
- Early diagnosis of solitary functioning kidney: comparing the prognosis of kidney agenesis and multicystic dysplastic kidney.Pediatric nephrology (Berlin, Germany) · 2024Article
- Preclinical Detection of Early Glomerular Injury in Children with Kidney Diseases-Independently of Usual Markers of Kidney Impairment and Inflammation.International journal of molecular sciences · 2024Article
- Müllerian anomalies in girls with congenital solitary kidney.Pediatric nephrology (Berlin, Germany) · 2024Article
- [Possibilities and limitations of national guidelines based on the example of pediatric urology guidelines from the Pediatric Urology Working Group of the Austrian Society for Urology and Andrology (ÖGU)].Urologie (Heidelberg, Germany) · 2024Review
- Congenital anomalies of the kidney and urinary tract: defining risk factors of disease progression and determinants of outcomes.Pediatric nephrology (Berlin, Germany) · 2023Review
Corrections and comments
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Authors and funding
25 authors at 13 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn recent years, several studies have been published on the prognosis of children with congenital solitary kidney (CSK), with controversial results, and a worldwide consensus on management and follow-up is lacking. In this consensus statement, the Italian Society of Pediatric Nephrology summarizes the current knowledge on CSK and presents recommendations for its management, including diagnostic approach, nutritional and lifestyle habits, and follow-up. We recommend that any antenatal suspicion/diagnosis of CSK be confirmed by neonatal ultrasound (US), avoiding the routine use of further imaging if no other anomalies of kidney/urinary tract are detected. A CSK without additional abnormalities is expected to undergo compensatory enlargement, which should be assessed by US. We recommend that urinalysis, but not blood tests or genetic analysis, be routinely performed at diagnosis in infants and children showing compensatory enlargement of the CSK. Extrarenal malformations should be searched for, particularly genital tract malformations in females. An excessive protein and salt intake should be avoided, while sport participation should not be restricted. We recommend a lifelong follow-up, which should be tailored on risk stratification, as follows: low risk: CSK with compensatory enlargement, medium risk: CSK without compensatory enlargement and/or additional CAKUT, and high risk: decreased GFR and/or proteinuria, and/or hypertension. We recommend that in children at low-risk periodic US, urinalysis and BP measurement be performed; in those at medium risk, we recommend that serum creatinine also be measured; in high-risk children, the schedule has to be tailored according to kidney function and clinical data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.