Evidence map›Paper›PMID 35716288›Full record

ReviewMolecular biology reports2022

Review article epithelial to mesenchymal transition‑associated microRNAs in breast cancer.

Hossein Javdani, Homa Mollaei, Farzaneh Karimi, Shiva Mahmoudi, Ali Farahi, Mohamad Javad Mirzaei-Parsa, Arman Shahabi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Trends in extracellular matrix biology.Molecular biology reports · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Hossein JavdaniMolecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Homa MollaeiDepartment of Biology, Faculty of Sciences, University of Birjand, Birjand, Iran.
Farzaneh KarimiDepartment of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Shiva MahmoudiDepartment of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Ali FarahiStudent Research Committee, Department of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Mohamad Javad Mirzaei-ParsaCell Therapy and Regenerative Medicine Comprehensive Center, Kerman University of Medical Sciences, Kerman, Iran.
Arman ShahabiCell Therapy and Regenerative Medicine Comprehensive Center, Kerman University of Medical Sciences, Kerman, Iran. a.shahabi@kmu.ac.ir.ORCID http://orcid.org/0000-0002-4612-6691
Kerman University of Medical Sciences · IRBirjand University of Medical Sciences · IRFerdowsi University of Mashhad · IRRafsanjan University of Medical Sciences · IRTabriz University of Medical Sciences · IRUniversity of Birjand · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite major advances, breast cancer (BC) is the most commonly diagnosed carcinoma and remains a deadly disease among women worldwide. Many researchers point toward an important role of an epithelial to mesenchymal transition (EMT) in BC development and promoting metastasis. Here, will be discussed that how functional changes of transcription factors, signaling pathways, and microRNAs (miRNA) in BC promote EMT. A thorough understanding the EMT biology can be important to determine reversing the process and design treatment approaches. There are frequent debates as to whether EMT is really relevant to BC in vivo, in which due to the intrinsic heterogeneity and tumor microenvironment. Nevertheless, given the importance of EMT in cancer progression and metastasis, the implementation of therapies against cancer-associated EMT will continue to help us develop and test potential treatments.

Indexed as

Breast NeoplasmsMicroRNAsEpithelial-Mesenchymal TransitionFemaleGene Expression Regulation, NeoplasticHumansTranscription FactorsTumor MicroenvironmentMicroRNAsTranscription FactorsEpithelial-mesenchymal transition. MicroRNAs. Breast cancer. Metastasis. cancer therapy

Identifiers

PMID35716288
OpenAlexW4283073368

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.