Evidence map›Paper›PMID 35717380›Full record

ReviewChinese medicine2022

Inflammatory bowel disease: an overview of Chinese herbal medicine formula-based treatment.

Shuo Yuan, Qi Wang, Jiao Li, Jia-Chen Xue, You Li, Huan Meng, Xiao-Ting Hou, Ji-Xing Nan, Qing-Gao Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Chinese medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Protective effects ofFrontiers in microbiology · 2026
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  4. Review
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  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shuo YuanKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China.
Qi WangChronic Disease Research Center, Medical College, Dalian University, Dalian, 116622, Liaoning, China.
Jiao LiChronic Disease Research Center, Medical College, Dalian University, Dalian, 116622, Liaoning, China.
Jia-Chen XueChronic Disease Research Center, Medical College, Dalian University, Dalian, 116622, Liaoning, China.
You LiChronic Disease Research Center, Medical College, Dalian University, Dalian, 116622, Liaoning, China.
Huan MengChronic Disease Research Center, Medical College, Dalian University, Dalian, 116622, Liaoning, China.
Xiao-Ting HouChronic Disease Research Center, Medical College, Dalian University, Dalian, 116622, Liaoning, China.
Ji-Xing NanKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China. jxnan@ybu.edu.cn.
Qing-Gao ZhangKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin, China. zhangqinggao@dlu.edu.cn.ORCID http://orcid.org/0000-0002-7140-3822
Yanbian University · CNDalian Medical University · CN

Funding

Korean Food Research Project 2017029National Natural Science Foundation of China 61671098
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic recurrent inflammatory disease of the intestine, including Crohn's disease (CD) and ulcerative colitis (UC), whose etiology and pathogenesis have not been fully understood. Due to its prolonged course and chronic recurrence, IBD imposes a heavy economic burden and psychological stress on patients. Traditional Chinese Herbal Medicine has unique advantages in IBD treatment because of its symptomatic treatment. However, the advantages of the Chinese Herbal Medicine Formula (CHMF) have rarely been discussed. In recent years, many scholars have conducted fundamental studies on CHMF to delay IBD from different perspectives and found that CHMF may help maintain intestinal integrity, reduce inflammation, and decrease oxidative stress, thus playing a positive role in the treatment of IBD. Therefore, this review focuses on the mechanisms associated with CHMF in IBD treatment. CHMF has apparent advantages. In addition to the exact composition and controlled quality of modern drugs, it also has multi-component and multi-target synergistic effects. CHMF has good prospects in the treatment of IBD, but its multi-agent composition and wide range of targets exacerbate the difficulty of studying its treatment of IBD. Future research on CHMF-related mechanisms is needed to achieve better efficacy.

Indexed as

AutophagyChinese herbal medicine formulaImmunityInflammatory bowel diseaseIntestinal mucosal barrierOxidative stress

Identifiers

PMID35717380
PMCPMC9206260
OpenAlexW4283068516

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.