Evidence map›Paper›PMID 35719010›Full record

Observational studyEuropean journal of neurology2022

Association of diabetes mellitus and admission glucose levels with outcome after endovascular therapy in acute ischaemic stroke in anterior circulation.

Kotryna Genceviciute, Martina B Göldlin, Christoph C Kurmann, Adnan Mujanovic, Thomas R Meinel, Johannes Kaesmacher, David J Seiffge, Simon Jung, Pasquale Mordasini, Urs Fischer and 8 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in European journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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  15. Development and validation of outcome prediction model for reperfusion therapy in acute ischemic stroke using nomogram and machine learning.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 2 countries.

Kotryna GenceviciuteDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Martina B GöldlinDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Christoph C KurmannInstitute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Adnan MujanovicInstitute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0002-6839-7134
Thomas R MeinelDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0002-0647-9273
Johannes KaesmacherInstitute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0002-9177-2289
David J SeiffgeDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0003-3890-3849
Simon JungDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0002-8288-6102
Pasquale MordasiniInstitute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Urs FischerDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0003-0521-4051
Jan GrallaInstitute of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Hakan SarikayaDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Barbara Goeggel SimonettiDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Kateryna AntonenkoDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0002-1936-5451
Roza M UmarovaDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0003-4451-679X
Lia BallyDepartment of Diabetes, Endocrinology, Clinical Nutrition, and Metabolism, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0003-1993-7672
Marcel ArnoldDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0002-4274-4644
Mirjam R HeldnerDepartment of Neurology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.ORCID 0000-0002-3594-2159
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeWe aimed to assess the association of diabetes mellitus (DM) and admission hyperglycaemia (AH), respectively, and outcome in patients with acute ischaemic stroke with large vessel occlusion in the anterior circulation treated with endovascular therapy (EVT) in daily clinical practice.

methodsConsecutive EVT patients admitted to our stroke centre between February 2015 and April 2020 were included in this observational cohort study. Patients with versus without DM and with versus without AH (glucose ≥ 7.8 mmol/L) were compared.

resultsWe included 1020 patients (48.9% women, median age = 73.1 years); 282 (27.6%) had DM, and 226 (22.2%) had AH. Patients with versus without DM less often showed successful reperfusion (odds ratio [OR]

conclusionsHyperglycaemia more than DM was associated with worse 3-month outcome in the patients studied, more likely so in the case of moderate/good collaterals and mismatch in admission imaging.

Indexed as

Brain IschemiaDiabetes MellitusEndovascular ProceduresHyperglycemiaIschemic StrokeStrokeAgedFemaleGlucoseHumansMaleThrombectomyTreatment OutcomeGlucoseacute ischaemic strokeadmission glucose levelsdiabetes mellitusendovascular therapyoutcome

Identifiers

PMID35719010
PMCPMC9544025
OpenAlexW4283156124

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.