Evidence map›Paper›PMID 35719155›Full record

ArticleFrontiers in nutrition2022

Malnutrition Is Highly Prevalent in Patients With Chronic Pancreatitis and Characterized by Loss of Skeletal Muscle Mass but Absence of Impaired Physical Function.

Mats L Wiese, Simone Gärtner, Nele von Essen, Julia Doller, Fabian Frost, Quang Trung Tran, Frank Ulrich Weiss, Fatuma Meyer, Luzia Valentini, Leif-A Garbe and 9 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04474743 (Multi-center, Controlled Cross-sectional Analysis of the Phenotype of Malnutrition in Patients With Liver Cirrhosis, Chronic Pancreatitis and Short Bowel Syndrome), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04474743 completednot on this map

Multi-center, Controlled Cross-sectional Analysis of the Phenotype of Malnutrition in Patients With Liver Cirrhosis, Chronic Pancreatitis and Short Bowel Syndrome (as Part of the Joint Project "Enteral Nutrition in Malnutrition Due to Diseases of the Gastrointestinal Tract: From Basic Understanding to an Innovative Treatment Concept" (EnErGie))

TypeobservationalSponsorUniversity Medicine GreifswaldRan2018 to 2021Enrolled345ConditionsLiver Cirrhoses, Chronic Pancreatitis, Short Bowel SyndromeArmsNo intervention - cross-sectional observational only
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Malnutrition and sarcopenia are associated with poor quality of life in Indian patients with chronic pancreatitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
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  7. Review
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 2 countries.

Mats L WieseDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Simone GärtnerDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Nele von EssenDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Julia DollerDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Fabian FrostDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Quang Trung TranDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Frank Ulrich WeissDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Fatuma MeyerInstitute of Evidence-Based Dietetics (NIED), University of Applied Sciences Neubrandenburg, Neubrandenburg, Germany.
Luzia ValentiniInstitute of Evidence-Based Dietetics (NIED), University of Applied Sciences Neubrandenburg, Neubrandenburg, Germany.
Leif-A GarbeDepartment of Agriculture and Food Sciences, University of Applied Sciences Neubrandenburg, Neubrandenburg, Germany.
Cornelia C MetgesInstitute of Nutritional Physiology "Oskar Kellner", Research Institute for Farm Animal Biology (FBN), Dummerstorf, Germany.
Karen BannertDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock, Germany.
Lea Franziska SautterDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock, Germany.
Luise EhlersDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock, Germany.
Robert JasterDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock, Germany.
Georg LamprechtDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock, Germany.
Antje StevelingDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Markus M LerchDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Ali A AghdassiDepartment of Medicine A, University Medicine Greifswald, Greifswald, Germany.
Universitätsmedizin Greifswald · DEUniversity of Rostock · DENeubrandenburg University of Applied Sciences · DELudwig-Maximilians-Universität München · DEResearch Institute for Farm Animal Biology (FBN) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: Patients with chronic pancreatitis (CP) have an increased risk of malnutrition, a condition linked to reduced muscle mass and physical performance. We have investigated the risk factors, phenotypic presentation, and health implications associated with malnutrition in CP. Materials and Methods: In a multicenter cross-sectional study we recruited patients with confirmed CP and healthy volunteers as a control group. Malnutrition was diagnosed according to the criteria proposed by the Global Leadership Initiative on Malnutrition. We performed detailed examinations of body composition and physical function as well as testing of routine blood parameters and markers of inflammation. Results: We included 66 patients [mean (±SD) age: 56.0 (±14.5) years; 51 males] and an equal number of age- and sex-matched controls. Moderate malnutrition was diagnosed in 21% ( Conclusion: Malnutrition is a frequent complication of CP characterized by loss of skeletal muscle mass. As this condition becomes evident only at an advanced stage, regular testing for altered body composition is recommended. Suitable biomarkers and the link between loss of muscle mass and physical function require further investigation. Clinical Trial Registration: [https://clinicaltrials.gov/ct2/show/NCT04474743], identifier [NCT04474743].

Indexed as

chronic pancreatitisGLIMhandgrip strengthmalnutritionsarcopenia

Identifiers

PMID35719155
PMCPMC9202591
OpenAlexW4281658815

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.