Evidence map›Paper›PMID 35722136›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Therapeutic Benefits of Pomegranate Flower Extract: A Novel Effect That Reduces Oxidative Stress and Significantly Improves Diastolic Relaxation in Hyperglycemic In Vitro in Rats.

Yuanyuan Wei, Ahmad Taha Khalaf, Peng Ye, Wei Fan, Junyi Su, Wanlu Chen, Hao Hu, Rashid Menhas, Lifeng Wang, Zahraa Oglah

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Yuanyuan WeiCollege of Medicine, Chengdu University, Chengdu 610106, Sichuan, China.
Ahmad Taha KhalafCollege of Medicine, Chengdu University, Chengdu 610106, Sichuan, China.ORCID https://orcid.org/0000-0003-3831-2459
Peng YeDepartment of Anatomy and Histology, College of Medicine, Chengdu University, Chengdu 610106, Sichuan, China.ORCID https://orcid.org/0000-0002-2763-4690
Wei FanSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610106, Sichuan, China.
Junyi SuCollege of Medical, Fujian Medical University, Fuzhou 350108, Fujian, China.
Wanlu ChenDepartment of Anatomy and Histology, College of Medicine, Chengdu University, Chengdu 610106, Sichuan, China.
Hao HuDepartment of Anatomy and Histology, College of Medicine, Chengdu University, Chengdu 610106, Sichuan, China.
Rashid MenhasResearch Center of Sport Social Sciences, School of Physical Education and Sports, Soochow University, Suzhou, Jiangsu, China.
Lifeng WangDepartment of Physiology, Xinjiang Medical University, Urumqi 830011, Xinjiang, China.ORCID https://orcid.org/0000-0002-5563-8728
Zahraa OglahSchool of Science, Auckland University of Technology (AUT), 55 Wellesley Street East, Auckland, New Zealand.ORCID https://orcid.org/0000-0001-5663-9709
Chengdu University · CNAuckland University of Technology · NZChengdu University of Traditional Chinese Medicine · CNFujian Medical University · CNSoochow University · CNXinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pomegranate flower is an ancient herb in traditional Chinese medicine with multiple properties. Recent studies have shown that pomegranate flower extract is beneficial, especially for hyperglycemia. In this experiment, we investigated the diastolic effect of pomegranate flower polyphenol (PFP) extract on the isolated thoracic aorta of rats in both the absence and presence of high glucose levels. Isotonic contractile forces were recorded from aortic rings (about 3 mm in length) from rats using the BL-420F Biological Function Test System. Tissues were precontracted with 60 mM KCl to obtain maximum tension under 1.0 g load for 1 hour before the balance was achieved, and the fluid was changed every 15 minutes. PFP (700 mg/L-900 mg/L) showed a concentration-dependent relaxant effect on the aortic rings; vasodilation in the endothelium-intact was significantly higher than that in the de-endothelialized segments (

Identifiers

PMID35722136
PMCPMC9200500
OpenAlexW4285741972

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.