ArticleTrials2022
Assessing the impact of a novel house design on the incidence of malaria in children in rural Africa: study protocol for a household-cluster randomized controlled superiority trial.
Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04529434 (Star Homes - Better Health Through Better Housing), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Star Homes - Better Health Through Better Housing: Phase 2 House Evaluation
Who cites it
10 citing papers in PubMed.
- "The most stress comes from witnessing the abuse of children" -challenges faced by research assistants in community-based research in Mtwara, Tanzania.BMC public health · 2026Article
- Effect of a novel house (Star home) and toilet design on domestic fly densities in rural Tanzania.Parasites & vectors · 2025Article
- Healthy homes: Stakeholder perspectives on housing interventions to reduce environmentally mediated infections.PLOS global public health · 2025Article
- Community responses to a novel house design: A qualitative study of "Star Homes" in Mtwara, southeastern Tanzania.PloS one · 2025Article
- Acceptability of improved cook stoves-a scoping review of the literature.PLOS global public health · 2025Article
- Care seeking for childhood illnesses in rural Mtwara, south-east Tanzania: a mixed methods study.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2024Article
- The behaviour of adult Anopheles gambiae, sub-Saharan Africa's principal malaria vector, and its relevance to malaria control: a review.Malaria journal · 2024Review
- Spatial variation in housing construction material in low- and middle-income countries: A Bayesian spatial prediction model of a key infectious diseases risk factor and social determinant of health.PLOS global public health · 2024Article
- Understanding reticence to occupy free, novel-design homes: A qualitative study in Mtwara, Southeast Tanzania.PLOS global public health · 2023Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTraditional rural housing in hot, humid regions of sub-Saharan Africa usually consists of single-level, poorly ventilated dwellings. Houses are mostly poorly screened against malaria mosquitoes and limited airflow discourages the use of bednets resulting in high indoor transmission. This study aims to determine whether living in a novel design house with elevated bedrooms and permeable screened walls reduces malaria, respiratory tract infections, and diarrhoea among children in rural Tanzania. METHODS/STUDY
designThis is a household-randomized, controlled study in 60 villages in Mtwara, Tanzania. A total of 550 households are randomly selected, 110 of which are allocated a novel design house and 440 households continue to reside in traditional houses. A dynamic cohort of about 1650 children under 13 years will be enrolled and followed for 3 years, approximately 330 living in novel design houses and 1320 in traditional rural houses. The primary endpoint is the incidence of malaria; secondary endpoints are incidences of acute respiratory tract infections and diarrhoea diseases detected by passive and active surveillance. Exposure to malaria vectors will be assessed using light traps in all study houses. Structural, economic, and social science studies will assess the durability, cost-effectiveness, and acceptability of the new houses compared with traditional housing. Environmental data will be collected indoors and outdoors in study homes to assess the differences between house typologies. DISCUSSION: This is the first randomized controlled trial to assess the protective efficacy of a new house design targeting malaria in sub-Saharan Africa. The findings of this study could influence the future construction of homes in hot and humid zones of Africa.
trial registrationClinicalTrials.gov NCT04529434 . Registered on August 27, 2020.
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Registered trials
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