Trial reportInternational journal of obesity (2005)2022
Brain effect of bariatric surgery in people with obesity.
Trial report in International journal of obesity (2005), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT03414333. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Glucagon-like Peptide-1 (GLP-1) on Cognitive and Non-cognitive Function in Human
Open the trial in the graphWho cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Obesity-related differences in amygdala and hippocampal volume and metabolism before and after a placebo-controlled antidepressant trial in major depressive disorder.Scientific reports · 2026Trial
- Obesity and Cognitive Function: Leptin Role Through Blood-Brain Barrier and Hippocampus.Molecular neurobiology · 2025Review
- Psychiatric Comorbidities Associated with Food Addiction in Post-Bariatric Patients: Toward Personalized Mental Health Screening and Postoperative Care.Journal of personalized medicine · 2025Article
- Regional brain glucose uptake following gastric bypass surgery during normo- and hypoglycemic clamp: a pilot FDG-PET study.Endocrine · 2025Article
- State of the Science on Brain Insulin Resistance and Cognitive Decline Due to Alzheimer's Disease.Aging and disease · 2024Review
- Cognitive functioning in adolescents with severe obesity undergoing bariatric surgery or intensive non-surgical treatment in Sweden (AMOS2): a multicentre, open-label, randomised controlled trial.EClinicalMedicine · 2024Article
- Impact of Bariatric Surgery on Circulating Metabolites and Cognitive Performance.Obesity surgery · 2024Article
- Kinetic Modeling of Brain [Metabolites · 2024Article
- Sustained improvements in brain health and metabolic markers 24 months following bariatric surgery.Brain communications · 2024Article
- Applying Dynamical Systems Theory to Improve Personalized Medicine Following Mild Traumatic Brain Injury.Neurotrauma reports · 2024Article
- Near-Infrared Spectroscopy: A Free-Living Neuroscience Tool to Better Understand Diabetes and Obesity.Metabolites · 2023Review
- Obesity-Induced Brain Neuroinflammatory and Mitochondrial Changes.Metabolites · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesThe link between obesity and brain function is a fascinating but still an enigmatic topic. We evaluated the effect of Roux-en-Y gastric bypass (RYGB) on peripheral glucose metabolism, insulin sensitivity, brain glucose utilization and cognitive abilities in people with obesity. SUBJECTS/
methodsThirteen subjects with obesity (F/M 11/2; age 44.4 ± 9.8 years; BMI 46.1 ± 4.9 kg/m
resultsRYGB resulted in significant weight loss (from 46.1 ± 4.9 to 35.3 ± 5.0 kg/m
conclusionsBariatric surgery improves CMRg directly related to a better cognitive testing result. This study highlights the potential pleiotropic effects of bariatric surgery. TRIAL REGISTRY NUMBER: NCT03414333.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.