Evidence mapPaperPMID 35729420Full record

ReviewDiabetologia2022

The role of mental disorders in precision medicine for diabetes: a narrative review.

Sanne H M Kremers, Sarah H Wild, Petra J M Elders, Joline W J Beulens, David J T Campbell, Frans Pouwer, Nanna Lindekilde, Maartje de Wit, Cathy Lloyd, Femke Rutters

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Diabetologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07212075 (Precision Subclassification of Mental Health in Diabetes), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07212075 recruitingnot on this mapstarted 2025, after this paper: background citation

Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups

TypeobservationalSponsorForschungsinstitut der Diabetes Akademie MergentheimRan2025 to 2027Enrolled1,809ConditionsDiabetes (DM), Diabete Mellitus, Diabete Type 1, Diabete Type 2
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Precision Medicine in Type 2 Diabetes Mellitus: Utility and Limitations.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 5 countries.

Sanne H M KremersEpidemiology and Data Science, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. s.kremers@amsterdamumc.nl.ORCID 0000-0002-1851-1488
Sarah H WildUsher Institute, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-7824-2569
Petra J M EldersAmsterdam Public Health Research Institute, Amsterdam, the Netherlands.ORCID 0000-0002-5907-7219
Joline W J BeulensEpidemiology and Data Science, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-4181-0937
David J T CampbellDepartment of Medicine, University of Calgary Cumming School of Medicine, Calgary, AB, Canada.ORCID 0000-0002-5570-3630
Frans PouwerDepartment of Psychology, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-8172-9818
Nanna LindekildeDepartment of Psychology, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-4212-6838
Maartje de WitAmsterdam Public Health Research Institute, Amsterdam, the Netherlands.ORCID 0000-0001-6029-5101
Cathy LloydSchool of Health, Wellbeing and Social Care, Faculty of Wellbeing, Education and Language Studies, Open University, Milton Keynes, UK.ORCID 0000-0002-8863-3069
Femke RuttersEpidemiology and Data Science, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-1008-678X
Amsterdam University Medical Centers · NLAmsterdam Neuroscience · NLSteno Diabetes Centers · DKThe Open University · GBUniversity Medical Center Utrecht · NLUniversity of Calgary · CAUniversity of Edinburgh · GBUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This narrative review aims to examine the value of addressing mental disorders as part of the care of people with type 1 and type 2 diabetes in terms of four components of precision medicine. First, we review the empirical literature on the role of common mental disorders in the development and outcomes of diabetes (precision prevention and prognostics). We then review interventions that can address mental disorders in individuals with diabetes or at risk of diabetes (precision treatment) and highlight recent studies that have used novel methods to individualise interventions, in person and through applications, based on mental disorders. Additionally, we discuss the use of detailed assessment of mental disorders using, for example, mobile health technologies (precision monitoring). Finally, we discuss future directions in research and practice and challenges to addressing mental disorders as a factor in precision medicine for diabetes. This review shows that several mental disorders are associated with a higher risk of type 2 diabetes and its complications, while there is suggestive evidence indicating that treating some mental disorders could contribute to the prevention of diabetes and improve diabetes outcomes. Using technologically enabled solutions to identify mental disorders could help individuals who stand to benefit from particular treatments. However, there are considerable gaps in knowledge and several challenges to be met before we can stratify treatment recommendations based on mental disorders. Overall, this review demonstrates that addressing mental disorders as a facet of precision medicine could have considerable value for routine diabetes care and has the potential to improve diabetes outcomes.

Indexed as

Diabetes Mellitus, Type 2Mental DisordersHumansPrecision MedicineMental disordersMonitoringPersonalised medicinePrecision medicinePreventionPrognosticsReviewTreatmentType 1 diabetesType 2 diabetes

Identifiers

PMID35729420
PMCPMC9213103
OpenAlexW4283271147

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.