Evidence map›Paper›PMID 35732500›Full record

ArticleCold Spring Harbor molecular case studies2022

WP1066 induces cell death in a schwannomatosis patient-derived schwannoma cell line.

Abdulrahman Allaf, Berta Victoria, Rosa Rosario, Carly Misztal, Sakir Humayun Gultekin, Christine T Dinh, Cristina Fernandez-Valle

Open access · diamondAbstract read
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Abdulrahman AllafBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida 32816, USA.
Berta VictoriaBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida 32816, USA.
Rosa RosarioBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida 32816, USA.
Carly MisztalDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
Sakir Humayun GultekinDepartment of Pathology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
Christine T DinhDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
Cristina Fernandez-ValleBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida 32816, USA.
University of Central Florida · USUniversity of Miami · US

Funding

Preclinical Testing of PI3K Inhibitors for Vestibular SchwannomasR01DC017264 · NIDCD · UNIVERSITY OF CENTRAL FLORIDA · PI FERNANDEZ-VALLE, CRISTINA MARIA, LIU, XUE Z · 2018 to 2022
$3.1M
Co-targeting FAK and PI3K for NF2 SchwannomasR56NS102254 · NINDS · UNIVERSITY OF CENTRAL FLORIDA · PI FERNANDEZ-VALLE, CRISTINA MARIA · 2018 to 2018
$462k
NIDCD NIH HHS R01 DC017264NINDS NIH HHS R56 NS102254
6 · The paper itself

Abstract

Schwannomatosis is a rare genetic disorder that predisposes individuals to development of multiple schwannomas mainly in spinal and peripheral nerves and to debilitating chronic pain often unrelated to any schwannoma. Pathogenic variants of two genes,

Indexed as

NeurilemmomaNeurofibromatosesPyridinesSkin NeoplasmsTyrphostinsAdultCell DeathCell Line, TumorChildHumansTranscription FactorsLZTR1 protein, humanPyridinesTranscription FactorsTyrphostinsWP1066chronic painneoplasm of the peripheral nervous system

Identifiers

PMID35732500
PMCPMC9235848
OpenAlexW4283267435

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.