Evidence map›Paper›PMID 35734011›Full record

ArticlePublic health action2022

Integrating hepatitis C treatment into multidrug-resistant TB care.

O Kirakosyan, N Melikyan, J Falcao, N Khachatryan, H Atshemyan, I Oganezova, A Aznauryan, L Yeghiazaryan, N Sargsyants, A Hayrapetyan and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Public health action, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

O KirakosyanMédecins Sans Frontières (MSF), Yerevan, Armenia.
N MelikyanMédecins Sans Frontières (MSF), Yerevan, Armenia.
J FalcaoEpicentre, Paris, France.
N KhachatryanMédecins Sans Frontières (MSF), Yerevan, Armenia.
H AtshemyanMédecins Sans Frontières (MSF), Yerevan, Armenia.
I OganezovaMédecins Sans Frontières (MSF), Yerevan, Armenia.
A AznauryanMédecins Sans Frontières (MSF), Yerevan, Armenia.
L YeghiazaryanNational Tuberculosis Control Centre, Ministry of Health, Yerevan, Armenia.
N SargsyantsMédecins Sans Frontières (MSF), Yerevan, Armenia.
A HayrapetyanNational Tuberculosis Control Centre, Ministry of Health, Yerevan, Armenia.
S BalkanMSF, Paris, France.
C HewisonMSF, Paris, France.
H HuergaEpicentre, Paris, France.
Médecins Sans Frontières · FRNational Statistical Service of the Republic of Armenia · AMMinistry of Healthcare · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDirect-acting antivirals (DAAs) are not widely used for patients with chronic hepatitis C virus (HCV) infection and multidrug- or rifampicin-resistant TB (MDR/RR-TB). We describe the implementation aspects of a new integrated model of care in Armenia and the perceptions of the healthcare staff and patients.

methodsWe used qualitative methods, including a desktop review and semi-structured individual interviews with healthcare staff and with patients receiving HCV and MDR/RR-TB treatment.

resultsThe new integrated model resulted in simplified management of HCV and MDR/RR-TB at public TB facilities. Training on HCV was provided for TB clinic staff. All MDR/RR-TB patients were systematically offered HCV testing and those diagnosed with HCV, offered treatment with DAAs. Treatment monitoring was performed by TB staff in coordination with a hepatologist. The staff interviewed had a positive opinion of the new model. They suggested that additional training should be provided. Most patients were fully satisfied with the care received. Some were concerned about the increased pill burden.

conclusionIntegrating HCV treatment into MDR/ RR-TB care was feasible and appreciated by patients and staff. This new model facilitated HCV diagnosis and treatment among people with MDR/RR-TB. Our results encourage piloting this model in other settings.

Indexed as

DAAsdirect-acting antiviralsHCVintegrated careMDRTB

Identifiers

PMID35734011
PMCPMC9176196
OpenAlexW4283380366

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.