Evidence mapPaperPMID 35736645Full record

ReviewPathophysiology : the official journal of the International Society for Pathophysiology2022

Metabolomics and EMT Markers of Breast Cancer: A Crosstalk and Future Perspective.

Ajay Kumar Pal, Prateek Sharma, Alishan Zia, Deepali Siwan, Dipali Nandave, Mukesh Nandave, Rupesh K Gautam

Open access · goldAbstract readReview
In one paragraph

Review in Pathophysiology : the official journal of the International Society for Pathophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. 3‑Phenethyl-2-phenylquinazolin-4(3ACS pharmacology & translational science · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Omics-Based Investigations of Breast Cancer.Molecules (Basel, Switzerland) · 2023
    Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ajay Kumar PalDepartment of Pharmacology, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.
Prateek SharmaDepartment of Pharmacology, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.ORCID 0000-0001-5316-4023
Alishan ZiaDepartment of Pharmacology, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.
Deepali SiwanDepartment of Pharmacology, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.
Dipali NandaveDepartment of Dravyaguna, Karmavir V. T. Randhir Ayurved College, Boradi 425428, India.
Mukesh NandaveDepartment of Pharmacology, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.
Rupesh K GautamDepartment of Pharmacology, MM School of Pharmacy, Maharishi Markandeshwar University, Ambala 134007, India.ORCID 0000-0001-5580-5410
Delhi Pharmaceutical Science and Research University · INGovernment Ayurved College, Nanded · INMaharishi Markandeshwar University, Mullana · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cells undergo transient EMT and MET phenomena or vice versa, along with the parallel interplay of various markers, often correlated as the determining factor in decoding metabolic profiling of breast cancers. Moreover, various cancer signaling pathways and metabolic changes occurring in breast cancer cells modulate the expression of such markers to varying extents. The existing research completed so far considers the expression of such markers as determinants regulating the invasiveness and survival of breast cancer cells. Therefore, this manuscript is crosstalk among the expression levels of such markers and their correlation in regulating the aggressiveness and invasiveness of breast cancer. We also attempted to cover the possible EMT-based metabolic targets to retard migration and invasion of breast cancer.

Indexed as

breast cancer stem cells (BCSCs)chemoresistanceEMT-transcription factorsmetastasistriple-negative breast cancer (TNBC)tumor microenvironment

Identifiers

PMID35736645
PMCPMC9230911
OpenAlexW4281813675

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.