Evidence map›Paper›PMID 35737205›Full record

ArticleEuropean journal of epidemiology2022

Sex differences in the mortality rate for coronavirus disease 2019 compared to other causes of death: an analysis of population-wide data from 63 countries.

Pascal Geldsetzer, Trasias Mukama, Nadine Kamel Jawad, Tim Riffe, Angela Rogers, Nikkil Sudharsanan

Open access · bronzeAbstract read
In one paragraph

Article in European journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Pascal GeldsetzerDivision of Primary Care and Population Health, Department of Medicine, Stanford University, 1265 Welch Road, Stanford, CA, 94305, USA. pgeldsetzer@stanford.edu.ORCID http://orcid.org/0000-0002-8878-5505
Trasias MukamaHeidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-6520-5272
Nadine Kamel JawadStanford University School of Medicine, Stanford, CA, USA.
Tim RiffeLaboratory of Population Health, Max Planck Institute for Demographic Research, Rostock, Germany.ORCID http://orcid.org/0000-0002-2673-4622
Angela RogersDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Nikkil SudharsananHeidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-1710-4634
Stanford University · USGerman Cancer Research Center · DEHeidelberg University · DEIkerbasque · ESStanford Health Care · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Men are more likely than women to die due to coronavirus disease 2019 (COVID-19). An open question is whether these sex differences reflect men's generally poorer health and lower life expectancy compared to women of similar ages or if men face a unique COVID-19 disadvantage. Using age-specific data on COVID-19 mortality as well as cause-specific and all-cause mortality for 63 countries, we compared the sex difference in COVID-19 mortality to sex differences in all-cause mortality and mortality from other common causes of death to determine the magnitude of the excess male mortality disadvantage for COVID-19. We found that sex differences in the age-standardized COVID-19 mortality rate were substantially larger than for the age-standardized all-cause mortality rate and mortality rate for most other common causes of death. The excess male mortality disadvantage for COVID-19 was especially large in the oldest age groups. Our findings suggest that the causal pathways that link male sex to a higher mortality from a SARS-CoV-2 infection may be specific to SARS-CoV-2, rather than shared with the pathways responsible for the shorter life expectancy among men or sex differences for other common causes of death. Understanding these causal chains could assist in the development of therapeutics and preventive measures for COVID-19 and, possibly, other coronavirus diseases.

Indexed as

COVID-19Cause of DeathFemaleHumansLife ExpectancyMaleMortalitySARS-CoV-2Sex CharacteristicsCOVID-19GenderMortalitySARS-CoV-2Sex

Identifiers

PMID35737205
PMCPMC9219381
OpenAlexW4283327781

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.