Evidence mapPaperPMID 35739993Full record

ArticleAntioxidants (Basel, Switzerland)2022

Qiang Zhu, Xuanyou Liu, Qingyi Zhu, Zehao Liu, Chunlin Yang, Hao Wu, Linfang Zhang, Xiujuan Xia, Meifang Wang, Hong Hao and 6 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Oxidative Stress, Endothelial Dysfunction, andAntioxidants & redox signaling · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Qiang ZhuCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.ORCID 0000-0002-2567-5384
Xuanyou LiuCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.ORCID 0000-0002-5590-626X
Qingyi ZhuCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.
Zehao LiuCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.
Chunlin YangCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.
Hao WuCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.ORCID 0000-0001-6154-9759
Linfang ZhangCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.
Xiujuan XiaCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.
Meifang WangCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.
Hong HaoCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.
Yuqi CuiCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.ORCID 0000-0003-4225-5450
Guangsen ZhangInstitute of Molecular Hematopathy, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Michael A HillDalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211, USA.
Gregory C FlakerCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.
Shenghua ZhouDepartment of Cardiology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Zhenguo LiuCenter for Precision Medicine, Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.
University of Missouri · USCentral South University · CN

Funding

NIH HHS NIH HL124122
6 · The paper itself

Abstract

Critical limb ischemia (CLI) is a severe complication of diabetes mellitus that occurs without effective therapy. Excessive reactive oxygen species (ROS) production and oxidative stress play critical roles in the development of diabetic cardiovascular complications.

Indexed as

insulin resistancelimb ischemiaN-acetylcysteineoxidative stressreactive oxygen speciestype-2 diabetes

Identifiers

PMID35739993
PMCPMC9219773
OpenAlexW4281885782

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.