Evidence map›Paper›PMID 35740565›Full record

ArticleCancers2022

Epstein-Barr Virus (EBV) Is Mostly Latent and Clonal in Angioimmunoblastic T Cell Lymphoma (AITL).

Racha Bahri, François Boyer, Mohamad Adnan Halabi, Alain Chaunavel, Jean Feuillard, Arnaud Jaccard, Sylvie Ranger-Rogez

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Racha BahriMicrobiology Department, Faculty of Pharmacy, 87025 Limoges, France.
François BoyerUnité Mixte de Recherche CNRS (Centre National de la Recherche Scientifique) 7276 and INSERM (Institut National de la Santé et de la Recherche Médicale) U1262, 87025 Limoges, France.
Mohamad Adnan HalabiMicrobiology Department, Faculty of Pharmacy, 87025 Limoges, France.ORCID 0000-0001-8869-5385
Alain ChaunavelPathology Department, University Hospital Dupuytren, 87000 Limoges, France.
Jean FeuillardUnité Mixte de Recherche CNRS (Centre National de la Recherche Scientifique) 7276 and INSERM (Institut National de la Santé et de la Recherche Médicale) U1262, 87025 Limoges, France.
Arnaud JaccardUnité Mixte de Recherche CNRS (Centre National de la Recherche Scientifique) 7276 and INSERM (Institut National de la Santé et de la Recherche Médicale) U1262, 87025 Limoges, France.
Sylvie Ranger-RogezMicrobiology Department, Faculty of Pharmacy, 87025 Limoges, France.ORCID 0000-0002-4092-7164
Centre National de la Recherche Scientifique · FRHôpital Dupuytren · FRUniversité de Limoges · FR

Funding

Ligue contre le cancer NO
6 · The paper itself

Abstract

The Epstein-Barr virus (EBV) is associated with angioimmunoblastic T cell lymphoma (AITL), a peripheral T lymphoma of poor prognosis in at least 90% of cases. The role of EBV in this pathology is unknown. Using next-generation sequencing, we sequenced the entire EBV genome in biopsies from 18 patients with AITL, 16 patients with another EBV-associated lymphoma, and 2 controls. We chose an EBV target capture method, given the high specificity of this technique, followed by a second capture to increase sensitivity. We identified two main viral strains in AITL, one of them associated with the mutations

Indexed as

AITLangioimmunoblastic T cell lymphomaclonalEBVEpstein–Barr viruslatentNGS

Identifiers

PMID35740565
PMCPMC9221046
OpenAlexW4282582613

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.