Evidence map›Paper›PMID 35740867›Full record

ReviewBiomolecules2022

Gadolinium in Medical Imaging-Usefulness, Toxic Reactions and Possible Countermeasures-A Review.

Lennart Blomqvist, Gunnar F Nordberg, Valeria M Nurchi, Jan O Aaseth

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06551805 (Clinical Research Protocol of Ferumoxytol for Magnetic Resonance Enhancement Imaging in Patients With Atherosclerosis.), which is not on this map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06551805 recruitingnot on this mapstarted 2024, after this paper: background citation

Clinical Research Protocol of Ferumoxytol for Magnetic Resonance Enhancement Imaging in Patients With Atherosclerosis.

TypeobservationalSponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolRan2024 to 2026Enrolled100ConditionsAtherosclerosisArmsSafety assessment of Ferumoxytol., Assessment of the diagnostic value of Ferumoxytol for MR angiography.
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Adverse effects and underlying mechanism of rare earth elements.Environmental health : a global access science source · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Efficient and Specific PDGFRβ-Targeting Dual-Mode TAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Lennart BlomqvistDepartment of Molecular Medicine and Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden.
Gunnar F NordbergDivision of Sustainable Health, Department of Public Health and Clinical Medicine, Umeå University, SE-90187 Umeå, Sweden.ORCID 0000-0001-6938-7053
Valeria M NurchiDepartment of Life and Environmental Sciences, University of Cagliari, 09042 Cagliari, Italy.ORCID 0000-0002-4004-1988
Jan O AasethDepartment of Research, Innlandet Hospital Trust, P.O. Box 104, N-2381 Brumunddal, Norway.ORCID 0000-0002-7518-5703
Innlandet Hospital Trust · NOKarolinska University Hospital · SEUmeå University · SEUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gadolinium (Gd) is one of the rare-earth elements. The properties of its trivalent cation (Gd

Indexed as

GadoliniumKidney DiseasesChelating AgentsContrast MediaFibrosisHumansMagnetic Resonance ImagingChelating AgentsContrast MediaGadoliniumchelatescontrast induced nephropathygadoliniumgadolinium induced respiratory distress syndromegadolinium kineticsgadolinium toxicitynephrogenic systemic fibrosisside effects of gadolinium chelatestreatment of gadolinium toxicity

Identifiers

PMID35740867
PMCPMC9221011
OpenAlexW4281481345

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.