Evidence map›Paper›PMID 35741007›Full record

ArticleCells2022

Critical Requirements for the Initiation of a Cardiac Arrhythmia in Rat Ventricle: How Many Myocytes?

Aman Ullah, Minh Tuan Hoang-Trong, William Jonathan Lederer, Raimond L Winslow, Mohsin Saleet Jafri

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Aman UllahSchool of Systems Biology, Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA 22030, USA.
Minh Tuan Hoang-TrongSchool of Systems Biology, Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA 22030, USA.ORCID 0000-0002-2194-1737
William Jonathan LedererBiomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Raimond L WinslowInstitute for Computational Medicine and Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 20218, USA.
Mohsin Saleet JafriSchool of Systems Biology, Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA 22030, USA.ORCID 0000-0003-3174-1007
George Mason University · USUniversity of Maryland, Baltimore · USNortheastern University · US

Funding

Calcium Entrained ArrhythmiasR01HL105239 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JAFRI, MOHSIN SALEET, LEDERER, WILLIAM JONATHAN · 2011 to 2015
$4.9M
Multiscale spatiotemporal modeling of cardiac mitochondriaU01HL116321 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JAFRI, MOHSIN SALEET, LEDERER, WILLIAM JONATHAN · 2014 to 2018
$3.5M
NHLBI NIH HHS R01 HL105239NHLBI NIH HHS U01 HL116321
6 · The paper itself

Abstract

Cardiovascular disease is the leading cause of death worldwide due in a large part to arrhythmia. In order to understand how calcium dynamics play a role in arrhythmogenesis, normal and dysfunctional Ca

Indexed as

Calcium SignalingExcitation Contraction CouplingAnimalsArrhythmias, CardiacMyocytes, CardiacRatsSodium-Calcium ExchangerSodium-Calcium Exchangerarrhythmiacomputational modelheart failureventricular myocyte network

Identifiers

PMID35741007
PMCPMC9221049
OpenAlexW4281707063

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.