Evidence map›Paper›PMID 35741730›Full record

ArticleGenes2022

Retrogene Duplication and Expression Patterns Shaped by the Evolution of Sex Chromosomes in Malaria Mosquitoes.

Duncan Miller, Jianhai Chen, Jiangtao Liang, Esther Betrán, Manyuan Long, Igor V Sharakhov

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Duncan MillerDepartment of Entomology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Jianhai ChenDepartment of Ecology and Evolution, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-7278-8090
Jiangtao LiangDepartment of Entomology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.ORCID 0000-0002-8468-7457
Esther BetránDepartment of Biology, University of Texas at Arlington, Arlington, TX 76019, USA.ORCID 0000-0002-4742-7963
Manyuan LongDepartment of Ecology and Evolution, University of Chicago, Chicago, IL 60637, USA.
Igor V SharakhovDepartment of Entomology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.ORCID 0000-0003-0752-3747
University of Chicago · USVirginia Tech · USNational Research Tomsk State University · RUThe University of Texas at Arlington · US

Funding

Reference-quality Drosophila genome assemblies for evolutionary analysis of previously inaccessible genomic regionsR01GM116113 · NIGMS · UNIVERSITY OF ARIZONA · PI CLARK, ANDREW G, LONG, MANYUAN · 2016 to 2019
$2.3M
Improving genome assemblies for species of the Anopheles gambiae complexR21AI135298 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SHARAKHOV, IGOR V · 2018 to 2019
$440k
A chromosome-level genome assembly for the major African malaria vector Anopheles gambiaeR21AI159382 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SHARAKHOV, IGOR V · 2021 to 2022
$436k
NIAID NIH HHS R21 AI135298NIAID NIH HHS R21 AI159382NIGMS NIH HHS R01 GM116113NIH HHS R01GM116113
6 · The paper itself

Abstract

Genes that originate during evolution are an important source of novel biological functions. Retrogenes are functional copies of genes produced by retroduplication and as such are located in different genomic positions. To investigate retroposition patterns and retrogene expression, we computationally identified interchromosomal retroduplication events in nine portions of the phylogenetic history of malaria mosquitoes, making use of species that do or do not have classical sex chromosomes to test the roles of sex-linkage. We found 40 interchromosomal events and a significant excess of retroduplications from the X chromosome to autosomes among a set of young retrogenes. These young retroposition events occurred within the last 100 million years in lineages where all species possessed differentiated sex chromosomes. An analysis of available microarray and RNA-seq expression data for

Indexed as

AnophelesMalariaAnimalsFemaleMalePhylogenyRetroelementsSex ChromosomesRetroelementsAn. gambiaeAnopheles coluzziimalaria mosquitoesmale-biased expressionmeiotic sex chromosome inactivationretrogeneretropositionsex chromosome evolutionsexual antagonism

Identifiers

PMID35741730
PMCPMC9222922
OpenAlexW4281772385

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.