Evidence mapPaperPMID 35742776Full record

ArticleInternational journal of environmental research and public health2022

How Diabetes and Other Comorbidities of Elderly Patients and Their Treatment Influence Levels of Glycation Products.

Aleksandra Kuzan, Emilia Królewicz, Irena Kustrzeba-Wójcicka, Karolina Lindner-Pawłowicz, Małgorzata Sobieszczańska

Open access · goldFull text read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aleksandra KuzanDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0003-4264-8174
Emilia KrólewiczDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Irena Kustrzeba-WójcickaDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Karolina Lindner-PawłowiczClinical Department of Geriatrics, Wroclaw Medical University, 50-369 Wroclaw, Poland.ORCID 0000-0003-1732-1188
Małgorzata SobieszczańskaClinical Department of Geriatrics, Wroclaw Medical University, 50-369 Wroclaw, Poland.ORCID 0000-0003-4374-9866
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medical care for geriatric patients is a great challenge, mainly due to various overlapping deficits relevant to numerous coexisting diseases, of which the most common are diabetes mellitus and atherosclerosis. In the case of diabetes, the glycation process is intensified, which accelerates atherosclerosis development and diabetic complications. Our goal was to investigate the relationship between the classical biochemical parameters of diabetes and atherosclerosis, as well as parameters which may indicate a nephropathy, and the parameters strictly related to glycation, taking into account the pharmacological treatment of patients. Methods: We analyzed the patients' serum concentrations of fluorescent glycation product-pentosidine, concentrations of soluble receptors for advanced glycation products (sRAGE), lipoprotein receptor-1 (LOX-1), galectin 3 (GAL3), scavenger receptor class A (SR-A), and scavenger receptor class B (SR-BI), as well as the level of lipid peroxidation and free amine content. Among the identified correlations, the most interesting are the following: sRAGE with triglycerides (r = 0.47,

Indexed as

AtherosclerosisDiabetes Mellitus, Type 2MetforminAgedAminesGlycation End Products, AdvancedHumansInsulinReceptors, ScavengerScavenger Receptors, Class EAminesGlycation End Products, AdvancedInsulinMetforminReceptors, ScavengerScavenger Receptors, Class Eagingdiabetes mellitus type 2elderly diseasesgeriatric careglycation markers

Identifiers

PMID35742776
PMCPMC9223786
OpenAlexW4283265243

What Socratic holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.