Evidence map›Paper›PMID 35745263›Full record

ReviewNutrients2022

Immune System and Psychological State of Pregnant Women during COVID-19 Pandemic: Are Micronutrients Able to Support Pregnancy?

Alessio Alesci, Simona Pergolizzi, Angelo Fumia, Anthea Miller, Caterina Cernigliaro, Maria Zaccone, Vanessa Salamone, Enza Mastrantonio, Sebastiano Gangemi, Giovanni Pioggia and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Ascorbic acid intake during pregnancy.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2023
    Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Alessio AlesciDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy.ORCID 0000-0002-7580-8114
Simona PergolizziDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy.ORCID 0000-0002-6884-634X
Angelo FumiaDepartment of Clinical and Experimental Medicine, University of Messina, 98147 Messina, Italy.ORCID 0000-0001-5815-5302
Anthea MillerDepartment of Veterinary Sciences, University of Messina, 98168 Messina, Italy.
Caterina CernigliaroAzienda Sanitaria Provinciale 5 Messina, 98124 Messina, Italy.
Maria ZacconeAzienda Sanitaria Provinciale 5 Messina, 98124 Messina, Italy.
Vanessa SalamoneAzienda Sanitaria Provinciale 5 Messina, 98124 Messina, Italy.
Enza MastrantonioAzienda Sanitaria Provinciale 5 Messina, 98124 Messina, Italy.
Sebastiano GangemiDepartment of Clinical and Experimental Medicine, University of Messina, 98147 Messina, Italy.
Giovanni PioggiaInstitute for Biomedical Research and Innovation (IRIB), National Research Council of Italy (CNR), 98125 Messina, Italy.ORCID 0000-0002-8089-7449
Nicola CiceroDepartment of Biomedical and Dental Science and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-8055-1915
University of Messina · ITInstitute for Biomedical Research and Innovation · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune system is highly dynamic and susceptible to many alterations throughout pregnancy. Since December 2019, a pandemic caused by coronavirus disease 19 (COVID-19) has swept the globe. To contain the spread of COVID-19, immediate measures such as quarantine and isolation were implemented. These containment measures have contributed to exacerbate situations of anxiety and stress, especially in pregnant women, who are already particularly anxious about their condition. Alterations in the psychological state of pregnant women are related to alterations in the immune system, which is more vulnerable under stress. COVID-19 could therefore find fertile soil in these individuals and risk more severe forms. Normally a controlled dietary regimen is followed during pregnancy, but the use of particular vitamins and micronutrients can help counteract depressive-anxiety states and stress, can improve the immune system, and provide an additional weapon in the defense against COVID-19 to bring the pregnancy to fruition. This review aims to gather data on the impact of COVID-19 on the immune system and psychological condition of pregnant women and to assess whether some micronutrients can improve their psychophysical symptoms.

Indexed as

COVID-19PandemicsAnxietyDepressionFemaleHumansImmune SystemMicronutrientsPregnancyPregnant PeopleSARS-CoV-2Stress, PsychologicalMicronutrientsCOVID-19immune systemmicronutrientspregnancystressvitamins

Identifiers

PMID35745263
PMCPMC9227584
OpenAlexW4283122424

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.