Evidence map›Paper›PMID 35745628›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Model-Based Prediction of Acid Suppression and Proposal of a New Dosing Regimen of Fexuprazan in Humans.

Min-Soo Kim, Nora Lee, Areum Lee, Yoon-Jee Chae, Suk-Jae Chung, Kyeong-Ryoon Lee

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Updates in the Management of Erosive Esophagitis.The Journal of family practice · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Min-Soo KimCollege of Pharmacy, Seoul National University, Seoul 08826, Korea.ORCID 0000-0001-9229-4701
Nora LeeRIKEN Innovation Center, Research Cluster for Innovation, RIKEN, Yokohama 230-0045, Kanagawa, Japan.
Areum LeeDivision of Biopharmaceutics, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.
Yoon-Jee ChaeCollege of Pharmacy, Woosuk University, Wanju-gun 55338, Korea.ORCID 0000-0003-4921-4192
Suk-Jae ChungCollege of Pharmacy, Seoul National University, Seoul 08826, Korea.
Kyeong-Ryoon LeeLaboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Korea.ORCID 0000-0003-2175-8876
Seoul National University · KRKorea Research Institute of Bioscience and Biotechnology · KRKyung Hee University · KRWoosuk University · KR

Funding

Korea Research Institute of Bioscience and Biotechnology KGM5212221Ministry of Trade, Industry and Energy 20009774
6 · The paper itself

Abstract

Fexuprazan is a potassium-competitive acid blocker (P-CAB). The compounds in this newly developed drug family suppress intragastric acidity. As there are already other acid-suppressing drugs on the market, such as H

Indexed as

DWP14012fexuprazanmodel-informed drug developmentpharmacodynamic modelingpharmacokinetic modelingpotassium-competitive acid blocker

Identifiers

PMID35745628
PMCPMC9230547
OpenAlexW4281777619

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.