Evidence map›Paper›PMID 35745893›Full record

ReviewPolymers2022

Polymers Based on PLA from Synthesis Using D,L-Lactic Acid (or Racemic Lactide) and Some Biomedical Applications: A Short Review.

Juliene Oliveira Campos de França, Deborah da Silva Valadares, Mateus Freitas Paiva, Sílvia Cláudia Loureiro Dias, José Alves Dias

Abstract readReview
In one paragraph

Review in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Exploring the pivotal role of hot melt extrusion technology in developing PLGA based novel drug delivery platforms for better therapeutic outcomes.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review
  5. Review
  6. Article
  7. Fermentative valorisation of agri-food residues: optimisation ofFrontiers in bioengineering and biotechnology · 2026
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Synthetic Polymers for Drug, Gene, and Vaccine Delivery.Polymer science & technology (Washington, D.C.) · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juliene Oliveira Campos de FrançaLaboratório de Catálise, Instituto de Química, Campus Universitário Darcy Ribeiro-Asa Norte, Universidade de Brasília, Brasília 70910-900, Brazil.ORCID 0000-0002-9145-2752
Deborah da Silva ValadaresLaboratório de Catálise, Instituto de Química, Campus Universitário Darcy Ribeiro-Asa Norte, Universidade de Brasília, Brasília 70910-900, Brazil.ORCID 0000-0002-3589-6500
Mateus Freitas PaivaLaboratório de Catálise, Instituto de Química, Campus Universitário Darcy Ribeiro-Asa Norte, Universidade de Brasília, Brasília 70910-900, Brazil.ORCID 0000-0001-5819-5574
Sílvia Cláudia Loureiro DiasLaboratório de Catálise, Instituto de Química, Campus Universitário Darcy Ribeiro-Asa Norte, Universidade de Brasília, Brasília 70910-900, Brazil.ORCID 0000-0002-3351-9226
José Alves DiasLaboratório de Catálise, Instituto de Química, Campus Universitário Darcy Ribeiro-Asa Norte, Universidade de Brasília, Brasília 70910-900, Brazil.ORCID 0000-0003-0042-0091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly(lactic acid) (PLA) is an important polymer that is based on renewable biomass resources. Because of environmental issues, more renewable sources for polymers synthesis have been sought for industrial purposes. In this sense, cheaper monomers should be used to facilitate better utilization of less valuable chemicals and therefore granting more sustainable processes. Some points are raised about the need to study the total degradability of any PLA, which may require specific composting conditions (e.g., temperature, type of microorganism, adequate humidity and aerobic environment). Polymerization processes to produce PLA are presented with an emphasis on D,L-lactic acid (or rac-lactide) as the reactant monomer. The syntheses involving homogeneous and heterogeneous catalytic processes to produce poly(D,L-Lactic acid) (PDLLA) are also addressed. Additionally, the production of blends, copolymers, and composites with PDLLA are also presented exemplifying different preparation methods. Some general applications of these materials mostly dedicated to the biomedical area over the last 10-15 years will be pointed out.

Indexed as

blends of PLAcomposites of PDLLAD,L-lactidepoly(DL-lactide-co-polymer)poly(lactic acid)-PLApolymerization based on D,L-lactic acidstereo polymerization of D,L-lactic acid

Identifiers

PMID35745893
PMCPMC9229942

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.