Evidence map›Paper›PMID 35748533›Full record

ArticlePlant biotechnology journal2022

Advanced pathway engineering for phototrophic putrescine production.

Robert A Freudenberg, Luisa Wittemeier, Alexander Einhaus, Thomas Baier, Olaf Kruse

Open access · goldAbstract read
In one paragraph

Article in Plant biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Developing a media formulation to sustainFrontiers in bioengineering and biotechnology · 2025
    Article
  4. Article
  5. The MicroalgaeCells · 2024
    Review
  6. Article
  7. Article
  8. Green microalgaFrontiers in microbiology · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Putrescine Detected in Strains ofPathogens (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Robert A FreudenbergFaculty of Biology, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany.ORCID 0000-0002-2084-7706
Luisa WittemeierFaculty of Biology, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany.ORCID 0000-0002-3249-0441
Alexander EinhausFaculty of Biology, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany.ORCID 0000-0003-4713-3671
Thomas BaierFaculty of Biology, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany.ORCID 0000-0002-5226-3035
Olaf KruseFaculty of Biology, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany.ORCID 0000-0001-9874-382X
Bielefeld University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The polyamine putrescine (1,4-diaminobutane) contributes to cellular fitness in most organisms, where it is derived from the amino acids ornithine or arginine. In the chemical industry, putrescine serves as a versatile building block for polyamide synthesis. The green microalga Chlamydomonas reinhardtii accumulates relatively high putrescine amounts, which, together with recent advances in genetic engineering, enables the generation of a powerful green cell factory to promote sustainable biotechnology for base chemical production. Here, we report a systematic investigation of the native putrescine metabolism in C. reinhardtii, leading to the first CO

Indexed as

Carboxy-LyasesPutrescineAmino AcidsArginineCadaverineCarbon DioxideNylonsOrnithineOrnithine DecarboxylaseOxidoreductasesPolyaminesAmino AcidsArginineCadaverineCarbon DioxideCarboxy-LyasesNylonsOrnithineOrnithine DecarboxylaseOxidoreductasesPolyaminesPutrescineamine oxidaseChlamydomonas reinhardtiiCRISPR/Cas9microalgaornithine decarboxylasepolyamines

Identifiers

PMID35748533
PMCPMC9491463
OpenAlexW4283397926

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.