ReviewTransfusion2022
Platelet dysfunction after trauma: From mechanisms to targeted treatment.
Abstract readReview
In one paragraph
Review in Transfusion, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- The absence of ADAMTS13 improves early outcomes in an experimental model of trauma with uncontrolled hemorrhage.The journal of trauma and acute care surgery · 2026Article
- Diagnosis and management of post-transfusion purpura in the acute trauma setting: A case report.Transfusion · 2026Article
- Whole blood first resuscitation and association of blood product utilization based on mechanism of injury.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Lyophilized Synthetic Platelets: In Vitro Characterization and In Vivo Evaluation in Mouse Thrombocytopenia Model.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Platelet clotting defects in severe trauma identified by a whole blood microfluidic assay.Transfusion · 2026Article
- The effects of recombinant human activated factor VII and tranexamic acid on traumatic bleeding and mortality in mice.Research and practice in thrombosis and haemostasis · 2026Article
- A novel role for ADAMTS13 in hyperfibrinolysis after trauma-induced shockBritish journal of anaesthesia · 2026Article
- Viscoelastic Hemostatic Assays in the Management of Trauma-Induced Coagulopathy: A Clinical Update.Journal of clinical medicine · 2025Review
- CD63 Immunological Activation Versus Hemostatic Function: Platelet Alterations After Polytrauma.Current issues in molecular biology · 2025Article
- Article
- The role of factor V in trauma-induced coagulopathy: an observational and experimental study.Research and practice in thrombosis and haemostasis · 2025Article
- The Role of Platelet Dysfunctions in the Pathogenesis of the Hemostatic-Coagulant System Imbalances.International journal of molecular sciences · 2025Review
- High-dimensional analysis of injured patients reveals distinct circulating proteomic profiles in plasma vs. whole blood resuscitation.Cell reports. Medicine · 2025Article
- HMGB-1 as a predictor of major bleeding requiring activation of a massive transfusion protocol in severe trauma.Scientific reports · 2025Observational
- Microfluidic transection injury and high-shear thrombus formation demonstrate increased hemostatic efficacy of cold-stored platelets andFrontiers in bioengineering and biotechnology · 2025Article
- High-Dimensional Single-Cell Mass Cytometry Demonstrates Differential Platelet Functional Phenotypes in Infants With Congenital Heart Disease.Arteriosclerosis, thrombosis, and vascular biology · 2024Article
- Platelet Contribution and Endothelial Activation and Stress Index-Potential Mortality Predictors in Traumatic Brain Injury.International journal of molecular sciences · 2024Article
- Blood Transfusion for Major Trauma in Emergency Department.Diagnostics (Basel, Switzerland) · 2024Review
- Severe Trauma-Induced Coagulopathy: Molecular Mechanisms Underlying Critical Illness.International journal of molecular sciences · 2023Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Pieter H SloosDepartment of Intensive Care Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Paul VulliamyCentre for Trauma Sciences, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Cornelis van 't VeerCenter for Experimental and Molecular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Anirban Sen GuptaDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID 0000-0002-5773-0667
Matthew D NealPittsburgh Trauma and Transfusion Medicine Research Center and Division of Trauma and Acute Care Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Karim BrohiCentre for Trauma Sciences, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Nicole P JuffermansLaboratory of Experimental Intensive Care and Anesthesiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Derek J B KleinveldLaboratory of Experimental Intensive Care and Anesthesiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-6357-1471
Funding
Heteromutivalent Peptide-Lipid Nanoconstructs as Artificial Platelet AnaloguesR01HL121212 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI SEN GUPTA, ANIRBAN · 2014 to 2024
$4.1MMechanisms of platelet exosome-mediated acute chest syndrome in sickle cell diseaseR01HL141080 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NEAL, MATTHEW D, NOVELLI, ENRICO M · 2019 to 2022
$3.1MPlatelet-inspired Delivery System for Targeted Thrombolytic TherapyR01HL129179 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI SEN GUPTA, ANIRBAN · 2015 to 2018
$1.8MNHLBI NIH HHS R01 HL121212NHLBI NIH HHS R01 HL129179
Abstract
PubMed holds no abstract for this paper.
Indexed as
Blood Platelet DisordersBlood PlateletsHemostasisHumansPlatelet Transfusionhematology - plateletshemostasisplatelet transfusion
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.