Evidence map›Paper›PMID 35752719›Full record

ArticleSleep & breathing = Schlaf & Atmung2023

Associations of overnight changes in body composition with positional obstructive sleep apnea.

Nguyen Thanh Tung, Shang-Yang Lin, Hoang Ba Dung, Tran Phan Chung Thuy, Yi-Chun Kuan, Cheng-Yu Tsai, Chen-Chen Lo, Kang Lo, Wen-Te Liu, Hsiao-Chi Chuang

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Nguyen Thanh TungInternational Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Shang-Yang LinSleep Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Hoang Ba DungOtorhinolaryngology Department, Cho Ray Hospital, Ho Chi Minh City, Vietnam.
Tran Phan Chung ThuyOtorhinolaryngology Department, Faculty of Medicine, Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Yi-Chun KuanDepartment of Neurology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Cheng-Yu TsaiDepartment of Civil and Environmental Engineering, Imperial College London, London, UK.
Chen-Chen LoSleep Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Kang LoSleep Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Wen-Te LiuSleep Center, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan. lion5835@gmail.com.
Hsiao-Chi ChuangSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan. chuanghc@tmu.edu.tw.ORCID 0000-0003-4651-5192
Taipei Medical University-Shuang Ho Hospital · TWCho Ray Hospital · VNImperial College London · GBTaipei Medical University Hospital · TWVietnam National University Ho Chi Minh City · VN

Funding

Ministry of Science and Technology, Taiwan MOST 109-2314-B-038-093-MY3
6 · The paper itself

Abstract

purposeBody composition is considered to be associated with obstructive sleep apnea (OSA) severity. This cross-sectional study aimed to examine associations of overnight body composition changes with positional OSA.

methodsThe body composition of patients diagnosed with non-positional and positional OSA was measured before and after overnight polysomnography. Odds ratios (ORs) of outcome variables between the case (positional OSA) and reference (non-positional OSA) groups were examined for associations with sleep-related parameters and with changes in body composition by a logistic regression analysis.

resultsAmong 1584 patients with OSA, we used 1056 patients with non-positional OSA as the reference group. We found that a 1-unit increase in overnight changes of total fat percentage and total fat mass were associated with 1.076-fold increased OR (95% confidence interval (CI): 1.014, 1.142) and 1.096-fold increased OR (95% CI: 1.010, 1.189) of positional OSA, respectively (all p < 0.05). Additionally, a 1-unit increase in overnight changes of lower limb fat percentage and upper limb fat mass were associated with 1.043-fold increased OR (95% CI: 1.004, 1.084) and 2.638-fold increased OR (95% CI: 1.313, 5.302) of positional OSA, respectively (all p < 0.05). We observed that a 1-unit increase in overnight changes of trunk fat percentage and trunk fat mass were associated with 1.056-fold increased OR (95% CI: 1.008, 1.106) and 1.150-fold increased OR (95% CI: 1.016, 1.301) of positional OSA, respectively (all p < 0.05).

conclusionOur findings indicated that nocturnal changes in the body's composition, especially total fat mass, total fat percentage, lower limb fat percentage, upper limb fat mass, trunk fat percentage, and trunk fat mass, may be associated with increased odds ratio of positional OSA compared with non-positional OSA.

Indexed as

Sleep Apnea, ObstructiveBody CompositionCross-Sectional StudiesHumansPolysomnographySleepApnea–hypopnea index (AHI)ArousalBody fluidFat distributionMuscle distributionUpper airway

Identifiers

PMID35752719
OpenAlexW4283448365

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.