ArticleFrontiers in veterinary science2022
Transcriptomics-Based Study of Differentially Expressed Genes Related to Fat Deposition in Tibetan and Yorkshire Pigs.
Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 45 citations in OpenAlex.
- Tissue-specific epigenetic regulation of fat metabolism in pigs through integrated analysis of DNA methylation and gene expression networks.Journal of animal science and biotechnology · 2026Article
- Metabolomics and Transcriptomics Reveal the Effects of FermentedMetabolites · 2026Article
- Genetic Diversity Estimation and Genome-Wide Selective Sweep Analysis of the Bazhou Yak.Animals : an open access journal from MDPI · 2025Article
- Effects of Acorns on Subcutaneous Fat Deposition in Yuxi Black Pigs by Transcriptomic Analysis.Metabolites · 2025Article
- Insights into high-altitude adaptation and meat quality regulation by gastrointestinal metabolites in Tibetan and black pigs.Frontiers in veterinary science · 2025Article
- Transcriptome and Metabolome Insights into Key Genes Regulating Fat Deposition and Meat Quality in Pig Breeds.Animals : an open access journal from MDPI · 2024Article
- Article
- Effects of Acorns on Fatty Acid Composition and Lipid Metabolism in Adipose Tissue of Yuxi Black Pigs.Animals : an open access journal from MDPI · 2024Article
- Article
- Network Meta-Analysis: Effect of Cold Stress on the Gene Expression of Swine AdipocytesCurrent issues in molecular biology · 2024Article
- Characterization and Function Analysis of miRNA Editing during Fat Deposition in Chinese Indigenous Ningxiang Pigs.Veterinary sciences · 2024Article
- Comparative transcriptome analysis of longissimus dorsi muscle reveal potential genes affecting meat trait in Chinese indigenous Xiang pig.Scientific reports · 2024Article
- Differentially expressed platelet activation-related genes in dogs with stage B2 myxomatous mitral valve disease.BMC veterinary research · 2023Article
- Transcriptome analysis of the Bactrian camel (Camelus bactrianus) reveals candidate genes affecting milk production traits.BMC genomics · 2023Article
- Divergence of Liver Lipidomes in Tibetan and Yorkshire Pigs Living at Different Altitudes.Molecules (Basel, Switzerland) · 2023Article
- Comparative expression analysis of water buffalo (Frontiers in veterinary science · 2023Article
- Healthy Gut Microbiome Composition Enhances Disease Resistance and Fat Deposition in Tibetan Pigs.Frontiers in microbiology · 2022Article
- Integration of ATAC-seq and RNA-seq analysis identifies key genes affecting intramuscular fat content in pigs.Frontiers in nutrition · 2022Article
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8 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Fat deposition traits are one of the key factors in pig production and breeding. The fat deposition capacity of pigs mainly affects the quality of pork and pig productivity. The aim of this study was to analyze the differential expression of mRNA levels in dorsal adipose tissue of Tibetan and York pigs at different growth stages using transcriptomic data to estimate key genes that regulate fat deposition in pigs. The results showed that a total of 32,747 positively expressed genes were present in the dorsal adipose tissue of the two breeds. Differentially expressed gene (DEG) screening of multiple combinations between the two breeds yielded 324 DEGS. Gene ontology (GO) biofunctional enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses showed that these DEGS were mainly involved in lipid metabolic pathways, steroid biosynthetic pathways and lipid biosynthetic processes, sterol biosynthetic processes, brown adipocyte differentiation, and other pathways related to lipid deposition and metabolism. The results showed that ACACA, SLC2A4 and THRSP genes positively regulated the lipid deposition ability and CHPT1 gene negatively regulated the lipid deposition ability in pigs. The results of this experiment suggest a theoretical basis for further studies on the regulatory mechanisms of fat deposition in pigs.
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