ReviewComprehensive psychoneuroendocrinology2022
Fear, love, and the origins of canid domestication: An oxytocin hypothesis.
Review in Comprehensive psychoneuroendocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Coexisting With Humans: Genomic and Behavioral Consequences in a Small and Isolated Bear Population.Molecular biology and evolution · 2025Article
- Evolutionary divergence of facial muscle physiology between domestic dogs and wolves.Anatomical record (Hoboken, N.J. : 2007) · 2025Article
- Similarities and differences between dog-human and human-human relationships.Scientific reports · 2025Article
- Effects of human-animal interaction on salivary and urinary oxytocin in children and dogs.Psychoneuroendocrinology · 2024Article
- Article
- The genomic landscape of mammal domestication might be orchestrated by selected transcription factors regulating brain and craniofacial development.Development genes and evolution · 2023Article
- Review
- What made us "hunter-gatherers of words".Frontiers in neuroscience · 2023Article
- Love and fear: A special issue.Comprehensive psychoneuroendocrinology · 2022Article
- Oxytocin and vasotocin receptor variation and the evolution of human prosociality.Comprehensive psychoneuroendocrinology · 2022Article
- Oxytocin and love: Myths, metaphors and mysteries.Comprehensive psychoneuroendocrinology · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The process of dog domestication likely involved at least two functional stages. The initial stage occurred when subpopulations of wolves became synanthropes, benefiting from life nearby or in human environments. The second phase was characterized by the evolution of novel forms of interspecific cooperation and social relationships between humans and dogs. Here, we discuss possible roles of the oxytocin system across these functional stages of domestication. We hypothesize that in early domestication, oxytocin played important roles in attenuating fear and stress associated with human contact. In later domestication, we hypothesize that oxytocin's most critical functions were those associated with affiliative social behavior, social engagement, and cooperation with humans. We outline possible neurobiological changes associated with these processes and present a Siberian fox model of canid domestication in which these predictions can be tested. Lastly, we identify limitations of current studies on the neuroendocrinology of domestication and discuss challenges and opportunities for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.