Evidence map›Paper›PMID 35757107›Full record

ReviewMediators of inflammation2022

The Role of MicroRNAs in Hyperlipidemia: From Pathogenesis to Therapeutical Application.

Yu Xiang, Li Mao, Mei-Ling Zuo, Gui-Lin Song, Li-Ming Tan, Zhong-Bao Yang

Open access · goldAbstract readReview
In one paragraph

Review in Mediators of inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yu XiangThe Affiliated Changsha Hospital of Hunan Normal University, Changsha, 410006 Hunan, China.
Li MaoDepartment of Basic Medicine, Changsha Health Vocational College, Changsha, 410600 Hunan, China.
Mei-Ling ZuoThe Affiliated Changsha Hospital of Hunan Normal University, Changsha, 410006 Hunan, China.
Gui-Lin SongThe Affiliated Changsha Hospital of Hunan Normal University, Changsha, 410006 Hunan, China.
Li-Ming TanThe Affiliated Changsha Hospital of Hunan Normal University, Changsha, 410006 Hunan, China.
Zhong-Bao YangThe Affiliated Changsha Hospital of Hunan Normal University, Changsha, 410006 Hunan, China.ORCID https://orcid.org/0000-0002-1334-8386
Hunan Normal University · CNChangsha Hospital for Maternal and Child Health Care · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperlipidemia is a common metabolic disorder with high morbidity and mortality, which brings heavy burden on social. Understanding its pathogenesis and finding its potential therapeutic targets are the focus of current research in this field. In recent years, an increasing number of studies have proved that miRNAs play vital roles in regulating lipid metabolism and were considered as promising therapeutic targets for hyperlipidemia and related diseases. It is demonstrated that miR-191, miR-222, miR-224, miR-27a, miR-378a-3p, miR-140-5p, miR-483, and miR-520d-5p were closely associated with the pathogenesis of hyperlipidemia. In this review, we provide brief overviews about advances in miRNAs in hyperlipidemia and its potential clinical application value.

Indexed as

HyperlipidemiasMetabolic DiseasesMicroRNAsHumansLipid MetabolismMicroRNAsMirn140 microRNA, humanMIRN224 microRNA, human

Identifiers

PMID35757107
PMCPMC9232323
OpenAlexW4283072235

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.