ArticleFrontiers in cardiovascular medicine2022
Pre-transplant Type 2 Diabetes Mellitus Is Associated With Higher Graft Failure and Increased 5-Year Mortality After Heart Transplantation.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Impact of SGLT2 Inhibitors on Clinical Outcomes in Patients with Diabetes Mellitus Following Heart Transplantation: A Meta-analysis.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Pooled it
- Meta-Analysis of Durable Compared to Temporary Left Ventricular Assist Devices Compared to Venoarterial Extracorporeal Membrane Oxygenation for Bridging to Heart Transplantation or Treatment of Primary Graft Dysfunction.Reviews in cardiovascular medicine · 2025Pooled it
- Donor diabetes status impacts long-term survival in diabetic heart transplant recipients.JHLT open · 2026Article
- Pre-diabetes and Diabetes in Heart Transplant Recipients: Epidemiological Insights from a Decade-Long Study.International journal of endocrinology and metabolism · 2026Article
- Heart transplant outcomes in patients with substance use disorder history: a nationwide cohort study using high-dimensional propensity score matching.European heart journal. Quality of care & clinical outcomes · 2026Article
- Increased Pre-Transplant Carotid Intima-Media Thickness Is Associated with Early Post-Transplant Atrial Fibrillation, Stroke, and Reduced Survival After Heart Transplantation.Life (Basel, Switzerland) · 2025Article
- Pre-Transplant Heavy Smoking Is Associated with Reduced Survival After Heart Transplantation Due to Infection and Malignancy.Journal of clinical medicine · 2025Article
- Association of early post-transplant hyperglycaemia and diabetes mellitus on outcomes following heart transplantation.Diabetic medicine : a journal of the British Diabetic Association · 2025Article
- Who is the Candidate? The Heart Transplant Evaluation Process.Methodist DeBakey cardiovascular journal · 2025Review
- Empagliflozin Use in Cardiac Transplant Patients:Sultan Qaboos University medical journal · 2025Article
- ECMO as a bridge to heart transplantation: Insights into stratification by heart failure etiology.JHLT open · 2024Article
- Impact of pretransplant T2DM on left ventricular deformation and myocardial perfusion in heart transplanted recipients: a 3.0 T cardiac magnetic resonance study.Cardiovascular diabetology · 2024Article
- Heart Transplantation.Journal of clinical medicine · 2024Review
- Temporal trends and outcomes of heart transplantation in Spain (2002-2021): propensity score matching analysis to compare patients with and without type 2 diabetes.Cardiovascular diabetology · 2023Article
- The ABC of Heart Transplantation-Part 1: Indication, Eligibility, Donor Selection, and Surgical Technique.Journal of clinical medicine · 2023Review
- Oral Anticoagulants after Heart Transplantation-Comparison between Vitamin K Antagonists and Direct Oral Anticoagulants.Journal of clinical medicine · 2023Article
- Frequency, Risk Factors, and Clinical Outcomes of Late-Onset Atrial Flutter in Patients after Heart Transplantation.Journal of cardiovascular development and disease · 2022Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: Cardiac transplant recipients often suffer from type 2 diabetes mellitus (T2DM) but its influence on graft failure and post-transplant mortality remains unknown. The aim of this study was to investigate the long-term effects of pre-transplant T2DM in patients after heart transplantation (HTX). Methods: This study included a total of 376 adult patients who received HTX at Heidelberg Heart Center between 01/01/2000 and 01/10/2016. HTX recipients were stratified by diagnosis of T2DM at the time of HTX. Patients with T2DM were further subdivided by hemoglobin A1c (HbA1c ≥ 7.0%). Analysis included donor and recipient data, immunosuppressive drugs, concomitant medications, post-transplant mortality, and causes of death. Five-year post-transplant mortality was further assessed by multivariate analysis (Cox regression) and Kaplan-Meier estimator. Results: About one-third of all HTX recipients had T2DM (121 of 376 [32.2%]). Patients with T2DM showed an increased 5-year post-transplant mortality (41.3% versus 29.8%; Conclusion: Pre-transplant T2DM is associated with higher graft failure and increased 5-year mortality after HTX.
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